Heart inflammation cases in young men higher than expected after mRNA vaccines

Re:Heart inflammation cases in young men higher than expecte... by SketchySeaBeast on Thursday June 10, 2021 @02:48PM (#27464093)

But the Pfizer vaccine doesn't contain any of the virus, unless it's just the immune reaction to the spike protein that causes the problem?

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Re:Heart inflammation cases in young men higher than expecte... by krrrh on Thursday June 10, 2021 @04:07PM (#27465131)

The vaccine produces spike protein and some research suggests that the spike protein itself is the source of vascular system damage. There was a contention that the vaccine spike protein is designed to stay on the surface of infected cells and not freely circulate into the bloodstream in large quantities but we also just don’t know for certain. It could even have to do with how the vaccine is administered and whether it largely affects the lymph system or a large quantity makes its way into the bloodstream.

https://www.salk.edu/news-release/the-novel-coronavirus-spik...

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Re:Heart inflammation cases in young men higher than expecte... by lame-robot-hoax on Thursday June 10, 2021 @02:55PM (#27464196)

https://blogs.sciencemag.org/pipeline/archives/2021/05/04/sp...

Derek Lowe has a post that discusses this.

In short from what I remember, the vaccine is administered in the deltoid, so most of the spike proteins should remain there. Some may travel throughout the body, but overall it is much much less than a natural infection.

That’s why I’m curious to compare myocarditis rates after vaccination to those after infection, because from what we know, natural infection should result in a higher rate of myocarditis than vaccination.

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Re:Heart inflammation cases in young men higher than expecte... by michaelrubin on Thursday June 10, 2021 @09:56PM (#27468487)

Did they ever confirm this experimentally, or it is just speculation about how it should work? It does seem like spike protein traveling further through the body than we thought it would would explain this.

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Re:Heart inflammation cases in young men higher than expecte... by nicoburns on Thursday June 10, 2021 @04:06PM (#27465119)

> unless it's just the immune reaction to the spike protein that causes the problem?

If the problem is inflammation then that seems entirely plausible... I thought that an immune response was exactly what inflammation is

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Re:Heart inflammation cases in young men higher than expecte... by SketchySeaBeast on Thursday June 10, 2021 @05:09PM (#27465889)

But then it would be caused by untold number of things and not marked out as special.

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Re:Heart inflammation cases in young men higher than expecte... by numpad0 on Thursday June 10, 2021 @02:50PM (#27464129)

Maybe having immune system working hard somehow naturally puts strain on cardiovascular systems?

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Re:Heart inflammation cases in young men higher than expecte... by jerf on Thursday June 10, 2021 @02:55PM (#27464202)

A theory (far from proved, but certainly also nothing I'd consider "disproved") is that the spike protein itself may be dangerous, in which case injecting something into yourself that causes your body to deliberately produce it may not be an unmitigated good.

I don't think we have the data either way to be sure the spike protein is completely harmless, though obviously how dangerous it is is bounded by the fact that many people experience no ill effects. (That is, it obviously can't be super-ultra-deadly, because it's not killing everyone instantly. How dangerous it could possibly be is bounded by the fact that many people have received the vaccine.)

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Re:Heart inflammation cases in young men higher than expecte... by nicoburns on Thursday June 10, 2021 @04:06PM (#27465126)

Presumably the effect is also bounded by the fact that it can't reproduce.

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Re:Heart inflammation cases in young men higher than expecte... by SketchySeaBeast on Thursday June 10, 2021 @03:02PM (#27464284)

Wouldn't that lead to heart inflammation with pretty much every sickness then? And given that the vaccine side effects are often less than a common cold, I don't know if that's particularly compelling.

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Re:Heart inflammation cases in young men higher than expecte... by derbOac on Thursday June 10, 2021 @02:54PM (#27464185)

Along those lines, I am wondering how this compares to other non-SARS-CoV-2 vaccines.

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