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A comment on Millions Are Skipping Their Second Doses of Covid Vaccines. Parent comment

Re:Millions Are Skipping Their Second Doses of Covid Vaccines by T-A on Sunday April 25, 2021 @10:24AM (#26932920)
From the J&J trial results [1]:

Vaccine efficacy (VE) against central laboratory-confirmed moderate to severe/critical COVID19 across all geographic areas in which the trial was conducted was 66.9% (95% CI 59.0, 73.4) when considering cases occurring at least 14 days after the single-dose vaccination and 66.1% (55.0, 74.8) when considering cases occurring at least 28 days after vaccination.

I have seen estimates as low as 40-something % for single doses of the mRNA vaccines, but this may have been an underestimate caused by only considering the first two weeks after inoculation. Given enough time for immunity to fully set in, the real number may be over 90% [2].

HOWEVER, those numbers all refer to symptomatic disease. Prevention of hospitalization and death was 100% in the J&J trial.

[1] https://www.fda.gov/media/146217/download

[2] https://www.nejm.org/doi/full/10.1056/NEJMc2036242

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Re:Millions Are Skipping Their Second Doses of Covid Vaccines by xiphias2 on Sunday April 25, 2021 @10:34AM (#26933007)
There’s a big difference between 2 weeks and 1 month, we know that now. Also the main concerns of the article are long term protection and protection against new variants. Both of these issues can wait until more people are vaccinated, and again we don’t have long term data on J&J vaccine, and I don’t see why it would be better than the mRNA vaccines.
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