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Re:US agencies call for pause in Johnson & Johnson vaccine by hedora on Tuesday April 13, 2021 @11:49AM (#26793995)
Yeah. The US is apparently already at ~50% antibodies, not counting vaccination. So, there’s a floor on the upside of the vaccine: It did no more than halve deaths. We’re in the middle of a surge, and it looks like most of the remaining 50% will end up catching covid before being vaccinated, so the percentage saved by vaccination will continue to drop.

The ideal strategy without hindsight was conventional wisdom: Protect the vulnerable and stiff upper lip for the rest. That would have more than halved casualties.

With the benefit of hindsight, a 3 month shutdown while hospitals got their acts together (combined with protecting the vulnerable) would have roughly quartered the remaining deaths, but at far lower cost than the full shutdown.

This was predicted by some of the old-guard epidemiologists, which is why they were against the shutdown in the first place.

The cancel culture folks lumped them in with MAGA anti-vaxxers (I blame both sides) and got them censored by the big platforms. Here we are, with 100,000’s unnecessarily dead, trillions squandered, and many careers, businesses and educations ruined.

I suspect roughly zero people have learned a lesson from this. Hopefully I’m overly cynical.

Re:US agencies call for pause in Johnson & Johnson vaccine by URSpider94 on Tuesday April 13, 2021 @12:31PM (#26794910)
CDC data shows that more like 25% of Americans have antibodies to COVID, so your number is off by a factor of two. [https://covid.cdc.gov/covid-data-tracker/#national-lab]

Additionally, you make a few glib statements that don’t really check out - you say give hospitals three weeks to prepare - how? There’s been a lot made of hospitals getting ready, but for the most part, the limiting factor for covid treatment has been how many icu care teams are available. More ventilators don’t help much if there’s nobody to use them. Second, I’m not sure how you protect senior citizens when everyone else, including the people who provide their care, is swimming in a soup of COVID.

Re:US agencies call for pause in Johnson & Johnson vaccine by Izkata on Tuesday April 13, 2021 @03:15PM (#26797585)
Like a while bunch of places did in March and April last year: build emergency capacity during what was supposed to be only a short several-week lockdown. Instead, when the capacity went mostly unused during the lockdown, it was quietly dismantled and lockdowns continued.

Also, we knew by April last year that ventilators were a bad choice: Doctors were jumping to it because of a specific weird symptom (blood oxygen levels impossibly low), but they had to keep turning the ventilators to higher settings to get an effect - to the point it was causing further lung damage. There's a bunch of less damaging ways to get more oxygen into a patient they'd been shifting to: https://www.statnews.com/2020/04/08/doctors-say-ventilators-...

Re:US agencies call for pause in Johnson & Johnson vaccine by UncleOxidant on Tuesday April 13, 2021 @12:11PM (#26794461)
> With the benefit of hindsight, a 3 month shutdown while hospitals got their acts together (combined with protecting the vulnerable) would have roughly quartered the remaining deaths, but at far lower cost than the full shutdown.

Where was this "full shutdown" you speak of? Not anywhere in the US. In Wuhan, and some other Asian countries, sure.

Didn't we kind of have the 3 month shutdown-lite you're referring to? Mid-March through about June for most places were at varying levels of shutdown in the US. But recall things started opening up in June of 2020. And cases started rising again into July.

> The US is apparently already at ~50% antibodies, not counting vaccination.

Citation? That seems like about 3X the most optimistic numbers I've heard from credible sources.

Re:US agencies call for pause in Johnson & Johnson vaccine by hedora on Tuesday April 13, 2021 @03:43PM (#26798043)
As for shutdown vs shutdown lite: No; the economy didn’t completely reopen in July. The recommendations from March 2020 were for more strict targeted shutdown protocols, but over a shorter duration (Strict reverse quarantines for nursing homes, but only for a few months for example.). The idea was to get less vulnerable groups to herd immunity faster. I’m saying a general, country wide shutdown for three months, concurrently with a strict targeted lockdown for about 5-6 months would have been more effective and cheaper (and, we’d have been done by last August, as the parent of my other post suggested.)

Source for 50%: Wall street journal. We were above 33% (based on random sampling, not confirmed cases) a few months ago.

This one from Feb predicted herd immunity a bit too early. They ran one with updated numbers last week, but I can’t find it:

https://www.wsj.com/articles/well-have-herd-immunity-by-apri...

Re:US agencies call for pause in Johnson & Johnson vaccine by 1cvmask on Tuesday April 13, 2021 @12:10PM (#26794446)
And then we had excess deaths in NY State because Governor Cuomo FORCED nursing homes to take in infected patients! And then he gave immunity to the whole industry from liability if they didn’t take precautions.

And he became the darling of the media and even won an Emmy.

https://www.vanityfair.com/news/2021/03/cuomos-nursing-home-...

Re:US agencies call for pause in Johnson & Johnson vaccine by kaitai on Tuesday April 13, 2021 @08:56PM (#26801710)
As someone with a family member working in a hospital who still couldn't get reliable PPE after 3 months, I feel that you live in an entirely different universe than I do. Would that we would have lived in a country where PPE for nurses, physicians, and hospital workers were prioritized in summer 2020. Hah. Hospitals were not in a position to get their own; I saw them jockeying for shipments from China and Korea and it's just ludicrous to expect people to get their PPE in bidding wars that involve calling in favors from the chief cardiologist's wife's uncle who owns a factory in China.
Re:US agencies call for pause in Johnson & Johnson vaccine by croes on Tuesday April 13, 2021 @12:09PM (#26794418)
You can't really protect the vulnerable, especially when the vaccines wasn't developed. Any source for the 50% antibody claim?
Re:US agencies call for pause in Johnson & Johnson vaccine by Izkata on Tuesday April 13, 2021 @03:22PM (#26797687)
> You can't really protect the vulnerable, especially when the vaccines wasn't developed.

If true, then social distancing, masks, and lockdowns couldn't have done anything for the rest of us for the past year either.

The argument for "protect the vulnerable" is that these precautions could be more targeted and so, hopefully, more effective.

Re:US agencies call for pause in Johnson & Johnson vaccine by cujo on Tuesday April 13, 2021 @12:04PM (#26794298)
I suspect a lot of folks learned (in the US) is that if you have a president who politicizes a pandemic and shits the bed on leadership, the populous is screwed.

Let's not pretend that rational discourse was ever an option, and the media isn't the place for blame.

Re:US agencies call for pause in Johnson & Johnson vaccine by MockObject on Tuesday April 13, 2021 @12:16PM (#26794584)
I don't know. Seems like a sane, sober, professional, mature, and objective media would go quite far in moderating the overheated partisan rhetoric from politicians.
Re:US agencies call for pause in Johnson & Johnson vaccine by pionar on Tuesday April 13, 2021 @02:51PM (#26797198)
No, in the age of social media and the internet, the media is no longer a check or filter on partisan rhetoric from politicians.
Re:US agencies call for pause in Johnson & Johnson vaccine by Deregibus on Tuesday April 13, 2021 @12:34PM (#26794957)
Putting aside that these claims are presented without any evidence, “most” of 50% of the US population is a minimum of 82M people. ~31M have contracted COVID so far. That we’re going to see almost 3x the number of cases, concentrated in half the population, as we enter summer, and with 3-4M vaccines administered per day, is a pretty bold claim.
Re:US agencies call for pause in Johnson & Johnson vaccine by DiogenesKynikos on Tuesday April 13, 2021 @06:00PM (#26799906)
> The ideal strategy without hindsight was conventional wisdom: Protect the vulnerable and stiff upper lip for the rest.

China, Vietnam, Australia and New Zealand used strict lockdowns to eliminate community spread, and then largely opened things up again. People in those countries have been able to live much more normal lives than people elsewhere during the pandemic. With hindsight, that was clearly the correct strategy: eliminate the virus, then reopen and keep a hawk eye out for any new cases.

Re:US agencies call for pause in Johnson & Johnson vaccine by loveistheanswer on Tuesday April 13, 2021 @07:53PM (#26801211)
2/4 of those examples are affluent island nations with low population densities.

Another one of those examples has been actively censoring covid information from the start, and thus cannot be trusted.

As for Vietnam, it is an interesting case, and we don't have enough data to rule out cross reactivity or other factors playing a role.

Extrapolating these data points to the entire world with wildly varying sociological, biological, environmental, and countless other factors and saying this is clearly the correct (and implicity achieveable) strategy for all 8 billion people on the earth is at best hypothetical.

Re:US agencies call for pause in Johnson & Johnson vaccine by mywittyname on Tuesday April 13, 2021 @09:53PM (#26802073)
> As for Vietnam, it is an interesting case, and we don't have enough data to rule out cross reactivity or other factors playing a role.

They took shit seriously and everyone prepared the minute news reached them of a possible pandemic. A good friend of mine is from VN and he was shipping PPE back home to his parents around August or October of 2019.

I think most Americans don't realize how common pandemics have been in east Asia. To them, it's like preparing for any other natural disaster. It's like comparing the Michiganders response to a blizzard to that of Texans.

Re:US agencies call for pause in Johnson & Johnson vaccine by loveistheanswer on Wednesday April 14, 2021 @10:26AM (#26807517)
>how common pandemics have been in east Asia.

This is why we need more data about cross reactivity playing a role in the relatively favorable health outcomes in Asia and Africa compared to the rest of the world.

Re:US agencies call for pause in Johnson & Johnson vaccine by DiogenesKynikos on Tuesday April 13, 2021 @08:46PM (#26801619)
> 2/4 of those examples are affluent island nations with low population densities.

Australia and NZ have densely populated cities, and what does being an island have to do with anything? Countries can close their borders. In fact, Australian states closed their borders to one another.

> Another one of those examples has been actively censoring covid information from the start, and thus cannot be trusted.

You don't have to trust the government. Just ask people you know in China what's going on there. Things have been mostly open for a year now, with no sign of the virus (outside of a few localized outbreaks, which have been dealt with through local lockdowns and blanket testing of the population). China is not the black box that many people think it is.

> As for Vietnam, it is an interesting case, and we don't have enough data to rule out cross reactivity or other factors playing a role.

Vietnamese people are not somehow immune to SARS-CoV-2. They're susceptible, just like everyone else.

> Extrapolating these data points to the entire world

This is the wrong way to think about this. These aren't data points generated by some semi-random process. They're countries that effectively implemented a strategy that we know should work, based on the basic principles of epidemiology. The virus is spread between people who are in close proximity to one another. If you drastically reduce contacts between people, the virus has far fewer chances to spread, and the epidemic recedes. If you do that long enough, you get down to a small enough number of cases that you can trace every single one and snuff out the virus completely. After that, you have to have strict measures at the border in order to catch imported cases, and you have to do regular testing in the population to make sure you don't miss the beginnings of any new outbreak.

There's nothing to "extrapolate." The strategy works because of very basic principles of how the virus spreads. The only question is whether each county has the organizational capacity and societal will to carry this strategy out.

Re:US agencies call for pause in Johnson & Johnson vaccine by loveistheanswer on Wednesday April 14, 2021 @10:23AM (#26807469)
>question is whether each county has the organizational capacity and societal will to carry this strategy out.

Indeed, that's a critical question to the long term success of the strategy.

If the world is unable to put 8 billion people in solitary confinement (nevermind the disastrous effects that would cause) indefinitely until the virus is eliminated (nevermind the fact that we are incapabale of validating if it was actually completely erradicated), the virus is only going to pop back up.

There is no evidence of such a strategy working at scale across the world.

The scientists on the covid team at the WHO have said as much: lockdowns should only be used as a last resort to buy time to scale up health care resources. Should we listen to those scientists?

Re:US agencies call for pause in Johnson & Johnson vaccine by DiogenesKynikos on Wednesday April 14, 2021 @02:28PM (#26811083)
It's not indefinite. The longest lockdown in China was 76 days, in Wuhan. Elsewhere, it was significantly shorter. Because they had a strict lockdown early on, they have been living with far fewer restrictions than most of the world for about a year now.

> the virus is only going to pop back up.

It does indeed pop up every once in a while, because the borders can never be 100% sealed. There have been outbreaks in Beijing, Qingdao, border towns in Heilongjiang and Yunnan, and elsewhere. But the government is understandably on high alert, and these outbreaks were caught early enough to be stopped with local lockdowns, coupled with blanket testing of the population (i.e., testing everyone in a city in a few days).

There was a brief "second wave" in China this winter, in which an outbreak managed to spread to several cities, but it was ended with relatively short lockdowns and mass testing. The number of new infections per day peaked around 100.

The basic lesson here is that you can both have near-zero case counts and let people live their lives almost as normal if you first act decisively to bring cases to zero, by using temporary, strict lockdowns, quarantines and mass testing.

> There is no evidence of such a strategy working at scale across the world.

China is the largest country in the world, so I'd call that "at scale." Vietnam is larger than any EU country. We're not talking about San Marino or Monaco here.

> The scientists on the covid team at the WHO have said as much: lockdowns should only be used as a last resort to buy time to scale up health care resources. Should we listen to those scientists?

A lot of recommendations will be reevaluated after the pandemic is over. Nothing like this has happened in 100 years.

Re:US agencies call for pause in Johnson & Johnson vaccine by captainredbeard on Wednesday April 14, 2021 @11:15AM (#26808262)
> The cancel culture folks lumped them in with MAGA anti-vaxxers (I blame both sides)

Agreed

Re:US agencies call for pause in Johnson & Johnson vaccine by cma on Tuesday April 13, 2021 @01:32PM (#26795932)
Something close to a full shutdown was done in China, etc., not Florida.