AZ has genuinely fucked up a couple times. They accidentally gave some trial participants half the intended dose

That was an Oxford fuck up, as were most of the other early clinical trial ones as far as we know. As others have explained, this is not a normal small organization plus Big Pharma arrangement, and after the EU went crazy I'll bet AZ is now regretting ever getting involved.

AZ's catastrophic fuck up from that testing mistake which should have burned a lot of their credibility was to use that data which in the long term didn't pan out to make a blended claim of higher efficacy than they could at that time legitimately support.

I agree, stuff like that should not happen.

This shouldn’t be downvoted it’s accurate. Several screw ups happened during the trials. AZ and Oxford are now paying the price for that lack of trust.