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Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by tw04 on Sunday February 14, 2021 @08:00PM (#26137859)
Who would volunteer for that study?

It would be horribly unethical to give people a placebo who didn't volunteer.

Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by mlyle on Sunday February 14, 2021 @08:09PM (#26137910)
I'd volunteer. I'm 41 and about to be up for my turn as an educator. I feel OK about the mitigations in my classroom and my overall level of risk, and a bit guilty about getting my dose earlier than most; a 50-50 chance of delaying my second dose doesn't appreciably make the risk picture worse.

If my second dose was delayed, odds are I'd end up with better long term immunity, too, even though my risk in the intermediate period would be higher.

> It would be horribly unethical to give people a placebo who didn't volunteer.

No shit. That's why I said "enroll" -- this includes getting consent. I suspect finding 20k people to volunteer out of the ~10M dosed per week wouldn't be that hard.

Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by xboxnolifes on Monday February 15, 2021 @03:36AM (#26140472)
The same kind of people who already enroll in any other kind of drug trial. "Who would volunteer for that study" doesn't make much sense of a question considering people are willing to do phase 0 studies of new drugs which are theoretically far more dangerous.
Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by Rebelgecko on Sunday February 14, 2021 @11:01PM (#26138923)
It could be beneficial for people that are further down the priority list and want to get vaccinated sooner. Especially since the people further down the list are less likely to die if they do get covid
Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by renewiltord on Sunday February 14, 2021 @08:43PM (#26138131)
I’d volunteer for a challenge trial, so obviously I’d volunteer for this.
Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by skybrian on Sunday February 14, 2021 @09:05PM (#26138257)
Why not volunteer? One dose is apparently quite protective already. Most likely, there will be little difference which arm of the trial you end up on.
Re:Half Doses of Moderna Vaccine Produce Neutralizing Antibo... by astura on Sunday February 14, 2021 @10:22PM (#26138697)
I would.