Re:The Mark Cuban Cost Plus Drug Company
by olyjohn on Wednesday January 27, 2021 @04:29PM
(#25934223)
Also your dog probably needs 1/10th the dose that an adult needs.
Re:The Mark Cuban Cost Plus Drug Company
by mattkrause on Wednesday January 27, 2021 @05:19PM
(#25934875)
It's way more complicated than that: there are differences in metabolism as well as size. It varies from drug to drug too, but as a rule of thumb dog needs about twice the human dose (in mg/kg). A 60 lb dog therefore needs about the same as a smallish adult.
Here's some FDA guidance on how to translate doses from animals to humans: https://www.fda.gov/media/72309/download
Re:The Mark Cuban Cost Plus Drug Company
by tguvot on Wednesday January 27, 2021 @09:21PM
(#25937299)
Even more than twice.
My dogs, despite weighting 5th of me had similar to mine dosages of antibiotics and antihistamines
Re:The Mark Cuban Cost Plus Drug Company
by philwelch on Wednesday January 27, 2021 @04:50PM
(#25934480)
Large dogs can be the same weight as small humans, so I'm not sure what accounts for 1/10th. Even medium-sized dogs like labs are about half the weight of a healthy, average-sized person.
Re:The Mark Cuban Cost Plus Drug Company
by girvo on Wednesday January 27, 2021 @05:19PM
(#25934869)
Depends on the drug, but their metabolism isnt identical to ours, and humans can often require significantly higher doses compared to other animals when controlling for dosage per weight unit. But again it depends and there is no hard and fast rule as far as I’m aware.
What I’m getting at is that for most animals the owner can be compensated for accidental death easily. (How much is a head of cattle at auction?)
Not that this explains all the discrepancy, but it may explain a non trivial percentage.