I've read that fatty tissue in the body triggers an increase in estrogen production, and that obesity can thus trigger a vicious cycle (insofar as estrogen triggers an increase in fatty tissue). Certainly, exposure to plastics and other environmental factors might increase estrogen levels alone, but given that we know that people (everywhere, I think) are fatter than they used to be, and that this seems significantly due to their being more sedentary and having worse diets (more processed foods, etc.), isn't that a plausible simple explanation? (Or at least one worth rigorously analyzing?)