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Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @07:44AM (#25159900)
Same. I'm not an anti-vaxxer or anything like that. But I think "don't use version 1.0" advice applies here just like it does for software. Especially given the possibility that things have been "hurried" in the name of expediency in terms of getting the vaccine(s) developed, tested, and approved.

The good news, in a sort of perverse sense, is that some delay to see what happens with "early adopters" is kinda inevitable anyway, due to the distribution logistics. Unless you're a health care provider, first responder, or in a high risk group, you'll probably have to wait a while to get access to the vaccine even if you want to take "version 1.0".

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by CalRobert on Friday November 20, 2020 @08:06AM (#25160068)
If the enemy is charging my base and someone offers me armor I'm not going to wait for all my fellow soldiers to try it out and see what happens.
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by montenegrohugo on Friday November 20, 2020 @08:35AM (#25160282)
Sounds like a reasonable position, until you extend the analogy: there is a slight, but nonetheless real chance that said armor has seriously adverse health effects on you. Maybe it spontaneously grows spikes and punctures your insides.

Additionally, you also have, as an individual, the option to just stand further back in the line. You don't have to get in immediate contact with the enemy, you can just go to the back of the army and wait for some time until the experimental armor is battle tested.

What sounds like the more rational choice (from an individual standpoint) now?

EDIT: not sure why this is getting downvotes. I do agree that the risk equation does seem leaning towards taking the vaccine. Tests have been conducted with >30.000 people, and so far it seems safe. There still exists of course a probability of that not being the case, but compared to the (known, and very real) side effects of covid, taking the vaccine asap even if it's version 1.0 seems like the sensible choice.

Still, parents analogy seemed flawed so I tried to extend it.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by aphextron on Friday November 20, 2020 @10:22AM (#25161285)
>"Sounds like a reasonable position, until you extend the analogy: there is a slight, but nonetheless real chance that said armor has seriously adverse health effects on you. Maybe it spontaneously grows spikes and punctures your insides."

Maybe it does. And maybe it will also turn me into a frog. But we can only deal with known knowns and known unknowns. You have to weigh that against the risk of COVID infection, multiplied by the misery of not being able to live a normal life.

I'll take the small, abstract, unknowable chance of something bad that has no known mechanism of action versus the empirically quantifiable reality of living in fear of COVID. These are unprecedented times, and we have to trust in science. It's gotten us this far.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @10:10AM (#25161146)
Still, parents analogy seemed flawed so I tried to extend it.

All analogies are flawed. That's why they are merely suggestive and not meant to be interpreted overly literally.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by dogma1138 on Friday November 20, 2020 @04:41PM (#25165374)
The issue here isn’t is the armor effective but would it explode and kill you without even being hit.

There have been plenty of mishaps with vaccines the last swine vaccine for example had severe side effects that caused disabilities.

When you plan to vaccinate millions of people even 1% of severe long term side effects is something you can’t afford.

Having the companies also being essentially exempt from future damages also complicates things because people might suffer from life altering side effects and would not be compensated for.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by Exmoor on Friday November 20, 2020 @01:43PM (#25163478)
I wonder if any software product managers ever conceived that in shipping software with known bugs to meet a deadline, they'd somehow be slightly eroding people's faith in vaccination science.

It's kind of wild when you think about it.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by JamesBarney on Friday November 20, 2020 @10:33AM (#25161404)
From all the data data we have it looks like the vaccine is orders of magnitude safer than the virus.

Yes vaccines can sometimes do weird things to the immune system, but viruses are far more likely to jack up the immune system than most vaccines.

[dead]
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by eplanit on Friday November 20, 2020 @09:19AM (#25160622)
We now know that Covid is not nearly as deadly as was first perceived, and that a relatively narrow band of the population is vulnerable to its worst effects.

It's foolish to act as though this is worse than it is.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by nwallin on Friday November 20, 2020 @02:49PM (#25164157)
The original estimates put COVID-19 at approximately 3-4%. At the time I'm writing this post, the United States has had 253,309 deaths from 11,789,304 cases, or 2.14%.

Without the lockdowns, without the mask mandates, without social distancing, without closing establishments where people congregate, COVID-19 easily overwhelms healthcare systems. We saw this play out in Wuhan, New York City, Italy, and elsewhere. When the healthcare capacity is overwhelmed, the results are catastrophic.

It's all well and good to say, "well, 2% isn't as bad as we thought." But that's not how it is. The problem is that with 10-20% of all patients requiring hospitalization, the hospitals can't keep up. Healthcare is a finite resource. It's not just the COVID patients who suffer, it's everybody who needs hospitalization for anything.

It is foolish to act as though this isn't as bad as it is.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by StillBored on Friday November 20, 2020 @10:31AM (#25161385)

  We now know that Covid is not nearly as deadly as was first perceived
That seems to depend on where you live. The 250k deaths from 11M infections number in the US is putting it within the original estimates. If you assume the actual case count is 2x or 3x the tested positive number, then its still roughly 1%, which will result in a lot of early deaths. If your over 50 then you should be taking it very seriously.

If the vaccine numbers are right, it could literally save over a million peoples lives just in the US.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by smaddox on Friday November 20, 2020 @01:36PM (#25163393)
1917 people died from COVID-19 yesterday in the US, alone. That's a 9/11 of deaths every 36 hours. It might not be as deadly as was first feared, but it is deadly.
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @09:39AM (#25160800)
You would be foolish not to get vaccinated given what we know about COVID.

Nobody said anything about not getting vaccinated. The point of discussion here is about not rushing to do it the first day the vaccine is available.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by ghaff on Friday November 20, 2020 @01:21PM (#25163244)
So if not Day 1, when? 6 months out, 1 year out, 2 years out, 10 years out? What arbitrary standard should those who are concerned about long-term effects apply?
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @08:04PM (#25167013)
That's up to the individual to decide. I'm not trying to be prescriptive here: I"m talking about what I would do. If you want the vaccine on Day 0, by all means, do it. Risk tolerance is obviously a very personal and subjective thing, so "you do you".
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by rayiner on Friday November 20, 2020 @07:58AM (#25159996)
> But I think "don't use version 1.0" advice applies here just like it does for software.

No it doesn’t, because vaccine development is more like bridge building than software development.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @10:08AM (#25161123)
https://en.wikipedia.org/wiki/Tacoma_Narrows_Bridge_(1940)

It was fine... until it wasn't (four months later). Anyway, this analogy is silly. Neither software nor bridges is exactly like the human body and the myriad of complex interactions that happen within.

At the end of the day, all I'm saying is that A. under normal circumstances, it takes a lot of time to get a vaccine tested and approved - for good reason. And B. these are not ordinary circumstances, there may be reason to think the process was rushed, and it may be prudent to not rush to be among the first to take the vaccine.

And just in case anybody misunderstands what I'm saying, let me reiterate as clearly as I can:

This is NOT an anti-vax screed, or an appeal to any conspiracy theories, or anything of that nature. And I am NOT suggesting anyone refuse to get vaccinated in the long-term. I am only suggesting a certain measure of patience, which is probably going to be part of the process anyway due to the logistics of distributing the vaccine.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by ghaff on Friday November 20, 2020 @01:18PM (#25163207)
As a somewhat nit, the Tacoma Narrows Bridge was known to have issues before construction was even finished although, obviously, it wasn't expected to fall down.

From your reference: "The original bridge received its nickname "Galloping Gertie" because of the vertical movement of the deck observed by construction workers during windy conditions. The bridge became known for its pitching deck, and collapsed into Puget Sound the morning of November 7, 1940, under high wind conditions. "

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by floatingatoll on Friday November 20, 2020 @10:37AM (#25161432)
You’re suggesting that people prioritize decisions based on individual uncertainty over decisions based on public good. That the logistics of distribution will result in the same outcome as your suggestion does not mitigate the perceived selfishness of your suggestion.
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by leetcrew on Friday November 20, 2020 @11:44AM (#25162137)
> You’re suggesting that people prioritize decisions based on individual uncertainty over decisions based on public good.

this is a simplistic and somewhat naive take. the decision to approve and distribute a covid vaccine is not going to be based solely on "public good". a vaccine has immense economic and political significance. it's not unreasonable to wonder how that might affect the approval process.

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by mindcrime on Friday November 20, 2020 @08:03PM (#25167004)
That the logistics of distribution will result in the same outcome as your suggestion does not mitigate the perceived selfishness of your suggestion.

I could not care less about anyone's opinion of my "perceived selfishness".

Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by Kye on Friday November 20, 2020 @08:09AM (#25160097)
Can you pull out the threads on that argument a little? Taken at face value, it's not meaningful. Bridges launch with huge, sometimes catastrophic problems.
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by unnouinceput on Friday November 20, 2020 @09:05AM (#25160511)
And that's exactly the point. Once it launches it either crashed down or stays up. As for this vaccine it got 30k tests. It's the equivalent of before launching said bridge the entire heavy machinery of the construction company stood on it and didn't collapsed.
Re:Pfizer submits Covid vaccine to FDA for approval, to dist... by brobdingnagians on Friday November 20, 2020 @09:44AM (#25160856)
The Italian bridge that collapsed after decades because of faulty assumptions about the concrete involved is a more accurate comparison. Assuming we know more than we do, and thinking it has no serious side effects because non have appeared in the first few months is not logically consistent.