Vaccine hopes rise as Oxford jab prompts immune response among old and young

Re:Vaccine hopes rise as Oxford jab prompts immune response ... by singemonkey on Monday October 26, 2020 @07:53AM (#24895122)

As well as acquiring immunity without being infectious.

However, the efficacy of this vaccine (and all the other candidates) still needs to be clarified - ie is it like a measles vaccination (~90% efficacy) or the flu vaccines (~ 25% - 50% I believe).

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Re:Vaccine hopes rise as Oxford jab prompts immune response ... by lbeltrame on Monday October 26, 2020 @08:03AM (#24895181)

For the FDA to even consider an emergency use authorization, they have put the following requirements:

- Efficacy of at least 60%

- Lower bound of efficacy (confidence interval) >= 30%

- Minimum safety data for at least one or two months post vaccination (I don't remember if it's one or two)

- At least five severe cases in the control arm

- Requirements for the trials to go on even if efficacy is found for an additional year after the trial end (for most of the trials, this means two years in total)

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Re:Vaccine hopes rise as Oxford jab prompts immune response ... by viraptor on Monday October 26, 2020 @08:01AM (#24895166)

Sounds right for the flu. I was curious about the details - here's a good starting point. https://www.cdc.gov/flu/vaccines-work/vaccineeffect.htm?CDC_...

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