Re:SARS-CoV-2 positivity rates associated with circulating V...
by tehjoker on Saturday September 19, 2020 @07:09PM
(#24530897)
The "therapeutic" dose of HCQ in COVID-19 patients is usually 600mg and up. The therapeutic dose for e.g. rheumatoid arthritis is 400mg or less. These higher doses were linked to arrhythmia and very little evidence of a beneficial effect has been found.
HCQ has been used in petri dishes against many viruses and been successful there. Whenever they use it in vivo, it fails. This is not a new phenomenon. The link below is somewhat dated at this point (May 2020), but I believe it still stands.
https://www.sciencedirect.com/science/article/abs/pii/S01663...
In any case, if the FDA is saying "may not" the drug is not a slam dunk even if it has some beneficial effect. Winning the rhetorical war on HCQ isn't going to make COVID go away or be less serious in a substantial fashion.
Re:SARS-CoV-2 positivity rates associated with circulating V...
by ColanR on Saturday September 19, 2020 @07:56PM
(#24531067)
> Winning the rhetorical war on HCQ
You said there's "no evidence". I said you were wrong, and apparently could muster better information than you could. That's not rhetoric, that's logic and evidence.
It's a well-understood drug, and any doctor worth their license would know how to use it safely.
> Revoked FDA use authorization
All that means is that more evidence is required before there's an official stamp of approval. "this drug may not be effective to treat COVID-19..." is what the actual request to revoke authroization said.
> Example of researches [sic] that doesn't see an effect of hydroxychloroquine
And there's other evidence contradicting that.
You said there's "no evidence" it's beneficial. That's pretty clearly false, merely based on what I already linked (maybe you should broaden your reading habits). We can debate the degree of confidence the accumulation of studies can give us, but that's outside both our leagues.