Going with just US figures the average spent on a computer in 2020 is 632 usd total. A high end card on the other hand is $400 to $800 each. a 2000-3000 pc with 800-1600 in graphics hardware is probably somewhat up there in the 99th percentile of configurations its pretty niche even so I cannot imagine any even technical challenges whatsoever with all the monitors hooked to the same GPU whereas a high end card ought to support 3 monitors.
So now are we talking about a 2000-3000 dollar pc with 2 dedicated GPUS with 4+ monitors?
Brief research seems to suggest this is challenging. Improving it would also seem not to benefit many users. Even talking merely about windows gamers only 1% used crossfire or sli.
There is even a plausible solution for people who want lots of displays so long as they are ok with a single gpu.
Although supporting 2 to 3 monitors is incredibly common there are actually cards which support 4-6.
For example
https://www.newegg.com/asrock-radeon-rx-5700-xt-rx-5700-xt-t...
There is probably no good solution for multiple GPUs + multiple displays because virtually nobody uses it now and longer term it seems even less will.
The logical decision is to go with the strongest single GPU with enough outputs for the monitors you plan to drive.
You CAN have a high end desktop. You can even have 3-6 monitors if it makes you happy. The only thing you cannot do is plug your monitors into the outputs of both GPUs. You must purchase GPUs wherein a single GPU has sufficient outputs and let the secondary GPU serve to aid in your favorite GPU compute or game playing adventure.
For example
https://www.newegg.com/gigabyte-radeon-rx-vega-64-gv-rxvega6...
This supports 6 displays and crossfire so it plays well with lots of displays and multiple GPU.
Stepping up further in price
https://www.newegg.com/evga-geforce-rtx-2080-super-08g-p4-32...
Supports 4 displays and SLI
Crossfire and SLI rely on a high speed interconnect and game specific support.
https://wiki.archlinux.org/index.php/NVIDIA/Tips_and_tricks#...
I guess if you need a thin client to your cloud services, linux desktop is great. Not really for lots of other things.