Things have different scaling laws. Very large rocket engines might not be practical for a range of reasons: wall thickness required to contain the high pressures (this is probably a big one) combined with the temperatures, combustion instability, controllability, and general ability to manufacture. Why are elephants and ants differently shaped? Another example is piston engines: large ones generally have lots of (relatively small compared to the overall displacement) cylinders rather than a couple of massive ones.

If a small number of rocket engines was required they would probably have a completely different design, perhaps an aerospike. Or maybe resurrecting Project Orion?