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Re:Low carb diet leads to “clinical remission” in 3 cases of... by vbtemp on Saturday June 20, 2020 @03:51PM (#23586638)
I was on a low-carb diet for a while. Loved it. Felt great. Was totally fit. All my digestive problems cleared up. I would never get "hangry". By every single subjective measure my quality of life and sense of well-being improved.

Then I got my cholesterol checked during a routine blood work and it was through the roof. WTF? Anyone know better than me about this?

Re:Low carb diet leads to “clinical remission” in 3 cases of... by PKop on Saturday June 20, 2020 @04:04PM (#23586788)
Your assumptions about high cholesterol being bad are wrong, simple as that. Just as a few decades ago, the popular (even as agreed upon within medical industry) assumptions about "low fat" were wrong.

In other words, the measurement you observed was good. Your brain needs that measured value you were tested at to be high. Your health would suffer if it wasn't.

There is tons of research and discussion about this online. The argument goes along with the idea that "statins" are one of the biggest pharmaceutical scams in history, bad for brain health and part of a larger false narrative on cholesterol.

Don't change a thing, you're doing it right.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @04:11PM (#23586839)
so. this is so general that it’s not helpful. what ranges are we talking about?

also, when people talk about cholesterol they usually don’t mean cholesterol they mean lipi-proteins that carry the cholesterol through the blood (cholesterol needs this as it’s hydrophobic). LDL from those lipo-proteins is definitely correlated with heart disease.

Here, read about it in more detail than you probably need to know: https://peterattiamd.com/the-straight-dope-on-cholesterol-pa...

Re:Low carb diet leads to “clinical remission” in 3 cases of... by PKop on Saturday June 20, 2020 @04:30PM (#23587020)
>this is so general that it’s not helpful

I think digging into the minutiae of specific numbers is silly, when the better frame is to construct the right diet the comports w/ human evolution and lifestyle, energy, activity and go from there.

Generally low carb (particularly avoiding high glycemic index carb, and sugars) preferring lower starch vegetables, while prioritizing animal fats, meat, fish.

Keto / keto carnivore, low carb etc have been around and well studied for a while now. People should do their own research (I like all of Gary Taubes' books and presentations, there are many others as well and podcasts) but ultimately I summarize the point as our bodies have evolved to follow this diet and observations of societies or time periods when one or the other was more prevalent show stark differentials in health, obesity, diabetes, metabolic syndrome...

I have no idea what my cholesterol numbers are (I'm sure they are "high"), but I certainly would never take a statin which would destroy my brain.. and as the OP mentioned, I know what makes me feel rested, energetic, what provides energy and muscle mass along with workouts in the weight room, what does or does not result in brain fog (sugar), better sleep, lower body fat, etc. All low carb / high fat. The more intense the exercise one does, the more carbs they can consume.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by firethief on Saturday June 20, 2020 @05:16PM (#23587364)
Keto diets have most definitely not been around long enough for anyone's bodies to evolve to follow them. That takes many thousands of years.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by eebynight on Saturday June 20, 2020 @05:40PM (#23587567)
Why would our bodies need to evolve to follow them when the mechanisms are already built-in?

Our body already contains the necessary pathways, enzymes and processes to switchover to utilizing fat as fuel. We quite literally evolved to do this...

That being said, I think this adaption was more of an energy conservation mode for when food was scarce rather than our ancestors intentionally eating in a ketogenic compatible manner.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by firethief on Monday June 22, 2020 @02:18PM (#23603677)
> That being said, I think this adaption was more of an energy conservation mode for when food was scarce rather than our ancestors intentionally eating in a ketogenic compatible manner.

Yeah, that's the point I was trying to make. I am aware that humans have the capability of surviving on a ketogenic diet, but that doesn't support the argument I was replying to that following such a diet is what we evolved to do.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by narag on Saturday June 20, 2020 @05:40PM (#23587565)
The diet of primitive humans was more similar to keto than to current developed country diets and it was in place for hundreds of thousands of years. The first big change was from agricultural civilizations in neolithic, less than ten thousands year ago. Current diet is at most a hundred years old. And specifically the diet that is causing so many problems is only fifty years old.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @06:34PM (#23587994)
primitive humans also lived 20-30 years tops. today at 20 you can eat whatever you want and you’ll mostly be fine short term.

i’m tired of people justifying their life choices by what primitive humans were doing. we’re not primitive humans.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by phonypc on Saturday June 20, 2020 @07:35PM (#23588367)
Life expectancy may have been that low, but overwhelmingly due to infant mortality. It's not like primitive humans were dying of old age in their 20s.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @08:05PM (#23588527)
not in their 20s but definitely not in their 80s like today. if you reached 50s you were a boss. a lot of things that we consider routine to fix today would have ended your life (broken leg/hand, infections, severe diarrhea, etc). We really under-appreciate how many things we have as tools to expand our lifespan today.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by phonypc on Saturday June 20, 2020 @08:57PM (#23588773)
From what I remember, it was more like if you made it past adolescence, making it to 50 was about normal. All kind of beside the point; you seemingly rejected the relevance of the primitive human diet based on their life expectancy. I don't think that follows.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by Aaronstotle on Saturday June 20, 2020 @08:36PM (#23588668)
Considering that soldiers in Ancient Greece could only retire after 30 years of service, I think it's fair to say there were plenty of 80 year old "primitive" humans.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by phonypc on Saturday June 20, 2020 @09:01PM (#23588797)
I think we're talking prehistory, pre-agriculture here.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Sunday June 21, 2020 @01:24AM (#23590051)
that what i also though. at least 10000 years ago if not more
Re:Low carb diet leads to “clinical remission” in 3 cases of... by firethief on Monday June 22, 2020 @02:21PM (#23603733)
Typical diets these days are pretty bad. But few, if any, societies of anatomically modern humans have lived under conditions where they would almost always be in ketosis, so evolutionary history doesn't provide a reason to think that we are best adapted to that being our normal state.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @04:44PM (#23587136)
i don’t like this line of thinking. digging in can help you tailor your diet and lifestyle on the genetics you have. also, decades of medical research cannot just be swept away based on a gut feeling. do know everything? no. do we have some good indicators? definitely.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by KerryJones on Saturday June 20, 2020 @04:16PM (#23586886)
LDL is correlated but not causative and it's been discovered that HDL is a much better indicator.

Take a look at this book: https://www.amazon.com/Big-Fat-Surprise-Butter-Healthy/dp/14...

It goes into it quite a bit more -- cholesterol is a _terrible_ indicator of overall health. This is well known in the Keto community.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @04:51PM (#23587189)
when you use LDL, HDL and cholesterol interchangeably this tells me that you don’t know what you’re talking about. Cholesterol itself is part of the lipid membrane of every cell. It’s essential. When people say “high cholesterol” they usually talk about high cholesterol carrying lipo-proteins in the bloodstream. high ldl is definitely a risk factor for CHD
Re:Low carb diet leads to “clinical remission” in 3 cases of... by eebynight on Saturday June 20, 2020 @05:43PM (#23587577)
How do you explain what Dave Feldman refers to as the lipid triad which is common in people that are on a low carbohydrate diet?

In this case, there is not sufficient evidence that those who have elevated HDL, LDL and low triglycerides have higher rates of cardiovascular disease...

https://cholesterolcode.com/a-dialog-on-the-lipid-triad-with...

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @08:07PM (#23588541)
not familiar with this fellow but if I had to guess I would say that in some cases ldl-c (volume) is high while ldl-p (count) is low leading the ldl not to cause as much damage as it a high number of particles
Re:Low carb diet leads to “clinical remission” in 3 cases of... by KerryJones on Monday June 22, 2020 @06:23PM (#23607592)
I didn't use them interchangeably...? Did you mean to refer to someone else?
Re:Low carb diet leads to “clinical remission” in 3 cases of... by krustyburger on Saturday June 20, 2020 @06:03PM (#23587745)
And the opposite is well known in the Whole Foods Plant-Based community.

I don’t have a horse in this race but appeals to authority when it comes to the science of diet are highly suspect.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by KerryJones on Monday June 22, 2020 @06:24PM (#23607616)
Nah, I used to be on a plant-based diet -- have done quite a bit of research. This is _not_ well known in the community, but sure, a few under-researched people in the group might say that has to do with it.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by JamesBarney on Saturday June 20, 2020 @05:14PM (#23587356)
Just an addendum to people who aren't familiar with medical research. This is way outside of mainstream medical practice, and 95% of researchers in the field believe cholesterol matters, statins have saved more lives than any other drug, and they improve cognition in most cases.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by eebynight on Saturday June 20, 2020 @05:32PM (#23587498)
You must not know too many people that have taken statins...

Sure, on paper, the LDL number goes down and according to the numbers you have a lower risk of heart attack, but the one common thing I've notice is that everyone complains that they feel terrible. Things like dizziness, nausea, low energy/libido, etc...

Let's not forget that it takes mainstream science time to catch up to new research. There is a lag in existing beliefs while more research is being done and evidence solidified.

That being said, lipidology is extremely complex but in the case of low carbohydrate diets the issue of having high LDL and HDL may not be as bad as mainstream medicine would make it out to be.

For some interesting insights on research being conducted in this field, Thomas Dayspring and Dave Feldman are extremely knowledgable and explain things quite well.

https://twitter.com/Drlipid

https://cholesterolcode.com/

They both have appeared on a number of health/fitness related podcasts but a quality one they both have been on is "The Drive" by Peter Attia:

https://peterattiamd.com/tomdayspring1/

https://peterattiamd.com/davefeldman/

edit: I would also argue that his subjective feelings of good health are a much better indicator than the population-averaged cholesterol numbers...

edit2: to say that this type of research is outside of mainstream medical advice is misleading. Lipodology is a prominent topic and a quick pubmed search for the "lipid" keyword since 2018 shows over 60k results. In medicine there is rarely a such thing as "settled" science. Things are continuously researched with new questions and information is used to update our original hypothesis. To refer to current advice as set in stone is very naive...

Re:Low carb diet leads to “clinical remission” in 3 cases of... by JamesBarney on Saturday June 20, 2020 @05:38PM (#23587548)
> That being said, lipidology is extremely complex but in the case of low carbohydrate diets the issue of having high LDL and HDL may not be as bad as mainstream medicine would make it out to be.

I'd 100% agree with this. But "your cholesterol sky rocketing a good sign" is not something the evidence currently shows.

> that everyone complains that they feel terrible. Things like dizziness, nausea, low energy/libido, etc...

Statins definitely have side effects, just on balance it leads to better cognitive outcomes instead of worse ones.

It's true that it takes time for mainstream science to catch up. But new preliminary research is new and preliminary and when it goes wrong it goes wrong more catastrophically than solid mainstream science.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by eebynight on Saturday June 20, 2020 @05:59PM (#23587708)
> I'd 100% agree with this. But "your cholesterol sky rocketing a good sign" is not something the evidence currently shows.

"sky-rocketing" is a definite over-exaggeration here.

I would be curious to see what your response is to the link I posted in another comment here.

I am wondering how people that still reference these dated outlooks on cholesterol can explain why there is insufficient evidence of higher cardiovascular disease rates in those with high LDL in the presence of high HDL and low triglycerides, commonly called the "lipid triad"?

https://cholesterolcode.com/a-dialog-on-the-lipid-triad-with...

What the parent comment initially stated would lead me to believe that he falls into this lipid triad group and if I was in his shoes I would tell any doctor that recommended a statin to f* off if I had just started feeling the best I'd ever had in my life.

Also, can you send me some research for your points about statins having an increase in cognitive function? My understanding was that many were arguing the opposite and some meta-reviews I read on the topic suggested that more evidence was needed to make any clear observations.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by labelbias on Tuesday June 23, 2020 @07:03AM (#23612338)
Masai all have atherosclerotic plaque build up and it is also present in their children. Childhood with plaque forces various adaptations to blood vessels. They get wider and more elastic to counter the reduced blood flow and rigidity.

Anyone who isn't a child won't be able to make these adaptations and anyone who isn't on a starvation mimicking diet but is trying to gain or maintain weight on diets filled with dietary cholesterol will almost certainly start building up plaque.

Yes, dietary cholesterol has a low effect on blood serum cholesterol after some amount. So yes, increasing the consumption of eggs from 5 to 10 a day won't linearly effect the blood serum cholesterol.

Problem with fasting mimicking diets is that they are not a cure and are not long-term.

Also, consuming only things that are easy to digest makes you digestion more fragile to varying stimuli in the future. Which is why people who are on these "rejuvinating" diets for a longer period of time tend to experience their disease symptoms much quicker when they go back to eating vegetables rich in antinutrients.

Here's a very nice study where all Masai participants had atherosclerosis. Some even died from heart disease being less than 20 years of age: https://academic.oup.com/aje/article-abstract/95/1/26/167903

"These pastoral people are exceptionally active and fit and they consume diets of milk and meat. The intake of animal fat exceeds that of American men. Measurements of the aorta showed extensive atherosclerosis with lipid infiltration and fibrous changes but very few complicated lesions. The coronary arteries showed intimal thickening by atherosclerosis which equaled that of old U.S. men. The Masai vessels enlarge with age to more than compensate for this disease. It is speculated that the Masai are protected from their atherosclerosis by physical fitness which causes their coronary vessels to be capacious."

Re:Low carb diet leads to “clinical remission” in 3 cases of... by Daynil on Saturday June 20, 2020 @04:49PM (#23587177)
There is an incredible amount of confusion surrounding cholesterol, mostly because of the incredible amount of bad/old/incomplete science around which many major medical associations base their recommendations.

To put it simply, using "cholesterol" as an indicator for anything is a completely oversimplified view originating in the 50s, when we didn't know enough molecular biology to know better. We've since moved on to breaking out LDL (bad) and HDL (good) cholesterol. However, as it turns out even that is too simplistic. There are further sub-classifications of LDL, such as large fluffy LDL and small dense LDL. If subclasifying LDL - Low-Density Lipoprotein - as "small and dense" seems counterintuitive, I agree. I feel like it's a result of the order in which we learned about all the forms of cholesterol, and a reflection of how complex the system is, and perhaps how much more we have left to fully understand it. As it turns out, so many of the perils of what we thought was caused by "high cholesterol", and then "high LDL/bad cholesterol" seem to be most strongly correlated with the small/dense LDL pattern. The irony is, we've been measuring everything but the main culprits, gaining an incomplete picture of what's actually going on, then ended up with wildly ineffective or harmful dietary recommendations as a result. A low fat high carb diet may reduce your cholesterol, but it can wreak havoc in so many other ways.

Bottom line is, eating a low carb, high fat diet increases all of your cholesterol (subject to individual variation), but seems to exert favorable effects on the overall ratio of the individual particles, which may be the important thing. If you're really interested in what's going on with your cholesterol, ask for a LDL particle size test, then you may be able to draw some more meaningful inferences. [1]

To me, it's a good hint that if every physical and mental aspect of your body improved on a diet, it's unlikely a bad thing. Best to discuss these things with your doctor though. Diet science is still a frustratingly murky field, so it's pretty hard to navigate right now. If you want to understand why, I highly recommend Good Calories, Bad Calories by Gary Taubes.

[1] http://education.questdiagnostics.com/faq/FAQ134

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @05:04PM (#23587296)
totally. looking at LDL-P is a better indicator that looking at “cholesterol”. There are cases where LDL-C looks okay but you have a large number of particles or cases with elevated LDL-C but with normal number of particles.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by enchiridion on Saturday June 20, 2020 @04:00PM (#23586741)
I've been on the keto diet for a while.

Two important pieces of info surround this.

1. Your body is burning more fat so it has to be mobilized in your blood.

2. Blood cholesterol is actually poorly correlated with cardiovascular health. Cholesterol plaques are actually a bandaid for the inflammation caused by a high carb diet. No inflammation no problem.

I am not a doc, so do your own research.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by KerryJones on Saturday June 20, 2020 @04:18PM (#23586910)
As many have said -- cholesterol is not indicative of much, HDL can be useful but still not much. First thing I would do is study a little bit about it, I found this book very informative, The Big Fat Surprise https://www.amazon.com/Big-Fat-Surprise-Butter-Healthy/dp/14...

I've been Keto for 18 months and it's changed my life (I've previous tried Paleo, Vegan, Vegetarian, Pescetarian, and a few others) -- I also got my blood tested 6 months after starting and I was in "perfect" levels according to the nurse -- but cholesterol specificaly is a terrible indicator.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by v37p on Saturday June 20, 2020 @03:57PM (#23586711)
Anecdotal, but the same happened to me. I later fixed it by running for 30 minutes 3x per week, and continue do to so to this day. LDL, HDL, Triglycerides, and blood pressure are all in the healthy ranges. 5.5 years and counting, with no "cheat" days either.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by jobu on Saturday June 20, 2020 @04:07PM (#23586805)
Yep. Exercise is the answer here. Moderate exercise will help your body to produce HDL cholesterol, which aids in removing unhealthy LDL and Triglycerides from your blood stream. According to my doctor, having a higher ratio of HDL to LDL cholesterol is far more important number than the total cholesterol level.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by heavyset_go on Saturday June 20, 2020 @04:15PM (#23586870)
I'm someone with a family history of CVD, so the only way I would try a low-carb diet is if I ate food that doesn't have clinical evidence for raising cholesterol, blood pressure, etc.

That meant eating only a small amount of saturated fat, and limiting palmitic acid in particular, and only small amounts of table salt balanced with other minerals like potassium chloride.

I'd eat a lot of salad, nuts, fish, and the only additional fat I'd eat would be in form of EVOO, avocado oil or other oils high in monounsaturated fats, and some polyunsaturated fats. My blood work was always fine.

Some people think low-carb means that they get to eat bacon for every meal and drink the grease.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by treeman79 on Saturday June 20, 2020 @05:55PM (#23587675)
Sounds like your following an AIP diet.

Fantastic for dealing with inflammation.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by NathanKP on Saturday June 20, 2020 @03:57PM (#23586710)
Yeah a lot of low carb diets replace sugar with super high cholesterol foods. It's not uncommon to hear keto influencers talking about how they can eat as much steak and bacon and cheese as they want.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by throwaway_USD on Saturday June 20, 2020 @05:02PM (#23587277)
>Then I got my cholesterol checked during a routine blood work and it was through the roof. WTF? Anyone know better than me about this?

Your LDL(bad), HDL (good) or both? And did your doctor do a coronary scan (checking for plaque build up)?

What you don't want is LDL Cholesterol building up as plaque in the arteries, there is some connection to plaque build up and LDL levels.

High HDL cholesterol is associated with low risk of heart disease.

Typically a LCHF diet raises HDL (i.e. lower risk of plaque build up and heart disease). In some people LCHF diets raise both LDL and HDL, but the ratios are typically and overall improvement (meaning less plaque build up). The goal with health isn't low cholesterol necessarily, its low plaque buildup.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by halfcat on Saturday June 20, 2020 @04:57PM (#23587246)
> Then I got my cholesterol checked during a routine blood work and it was through the roof. WTF? Anyone know better than me about this?

This is not necessarily a bad sign, but you should talk to your doctor about getting more advanced cholesterol blood tests.

There are different measures of cholesterol, like concentration per particle, number of particles, and size of particles, and regular bloodwork usually only measures one of those (concentration, I believe).

You can have a lot of small, empty particles, or fewer large, dense particles, and so forth. This means a regular test may not paint the whole picture, especially if you’re doing something “non-standard” like a keto diet, fasting, or if you’re losing significant body fat.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by shipman05 on Saturday June 20, 2020 @03:58PM (#23586721)
Low carb doesn't have to mean lots of meat, cheese, and fat. Most people would have positive outcomes from a diet that is 75% whole-food, plant-based no matter what the remaining 25% is.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by ardit33 on Saturday June 20, 2020 @04:04PM (#23586786)
Plants are mostly carbs yo...

well, some have more complex carbs... and some have more fat (avocados) and some have protein, but still "plant based diet" usually means complex carbs...

Healthier for sure, but it can't be considered 'low carb diet'

Re:Low carb diet leads to “clinical remission” in 3 cases of... by gshdg on Saturday June 20, 2020 @04:12PM (#23586845)
Not a ton of carb calories in lettuce, kale, spinach, broccoli, etc. They’re mostly composed of insoluble fiber (from which ruminants can extract calories but humans can’t) and water.

A “low carb” diet doesn’t exclude high amounts of insoluble fiber. It excludes high amounts of carbohydrate calories.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by ardit33 on Saturday June 20, 2020 @04:26PM (#23586982)
This is not getting through...

If you are consuming your 2000 calories diet, and it is coming from plants, you are still ingesting 2000 calories worth of carbs.....

1 kg of feathers, and 1 kg of iron, weight the same....

The feathers will be large and take more volume, while the iron will be small and more dense.

Same with foods.... if your plant based diet you are consuming 2000 worth of bio-available calories, then that is still mostly carbs...

It is healthier for sure than consuming 2000 calories through processed foods such a muffins, chips and other crap. But, still your 2000 CALORIES will come through CARBS, but they will be digested slowly due to the fiber.

But if you are ingesting 2000 bio-available calories through plants, it is most likely mostly carbs (plus some fats and protein). Insoluble fiber just goes towards your poop, and it is usually not counted under 'carbs'.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by heavyset_go on Saturday June 20, 2020 @04:34PM (#23587048)
Tofu, seitan, tempeh made without rice, etc are plant-based, high protein and low carb. Various fungi fall into the same category, although they aren't plants. Make a dish with vegetable oil and you'll have a high fat and protein meal with minimal carbs that is plant-based.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by ardit33 on Saturday June 20, 2020 @04:43PM (#23587127)
Makes sense, so are avocados, olives ect... (mostly fat), but you are essentially eliminating 90% of plants out there...

When you say Plant based diet, people assume lettuce, beans, tomatos, carrots, olives, broccoli, etc.. etc...

Re:Low carb diet leads to “clinical remission” in 3 cases of... by heavyset_go on Saturday June 20, 2020 @04:47PM (#23587157)
You eat those on the side, particularly lettuce, spinach, broccoli etc in as large of quantities as you'd like because they're low in carbs.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by gshdg on Sunday June 21, 2020 @08:21AM (#23591624)
Nope, in a low carb plant based diet, most of your calories tend to come from fats with some from protein.

There are plenty of fats in nuts and legumes, which are compatible with a low carb (even if not a zero carb) diet. Seeds are also rich in fats (and are the source of many vegetable oils).

Re:Low carb diet leads to “clinical remission” in 3 cases of... by NotHereNotThere on Saturday June 20, 2020 @04:19PM (#23586922)
How could you possibly eat 75% whole-food plants on a low carb diet?

Most of them (grains, legumes, fruits and nuts to a certain extent) would fall under high carb when eaten in those quantities

For me (and generally I'd say), low carb is <50g of carbs per day.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by nordsieck on Saturday June 20, 2020 @04:22PM (#23586949)
> How could you possibly eat 75% whole-food plants on a low carb diet?

It's basically not possible.

If you really want to eat a low carb plant based diet, you'd have to eat almost exclusively processed food like olive oil and Seitan.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by crazygringo on Saturday June 20, 2020 @04:10PM (#23586835)
Sorry but you're just completely factually wrong.

Potatoes, rice and bananas are whole-food, plant based, and are pretty much the highest carb you can go. And plants without starches and sugars simply don't have many calories at all. You can't survive on broccoli alone.

If you're doing low-carb and getting the calories you need, there's no physically possibly way to get those calories except through protein and fat -- they're literally the only other 2 macronutrients.

So yes, low carb always means lots of meat, cheese and/or fat. Or else you'd basically just be fasting.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by chillwaves on Saturday June 20, 2020 @04:24PM (#23586957)
The way you frame the third choice as "and/or fat" is disingenuous and undermines the whole comment.

Yes, vegetables are less calories dense. That doesn't mean meat/cheese/bacon have to be eaten. Just an easy example, avocado's are extremely calorie dense, and yes this means fat.

The issue I have is that you just categorize meat, cheese and fat together as if the only way to get fat is via those items, or as if fat itself were unhealthy. The second is just a myth, the first is a myth the person you are responding to is directly opposing.

It's not a great surprise that a diet restricting one of the three food macros will lean heavily on the other two groups.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by laser on Saturday June 20, 2020 @03:55PM (#23586688)
Hmmm iirc, and don’t take this as medical advice and do your own research/consult your doctor, but in states of ketosis in high fat diet, cholesterol rises but primarily in the form of HDL (high-density lipoprotein) while LDL (low-density lipoprotein) level drop. For heart disease, LDL is the concern as it’s floaty and thus gets stuck and accumulates in arteries, while HDL is considered more “good/harmless” as it doesn’t do that.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by jklehm on Saturday June 20, 2020 @04:02PM (#23586761)
You may be one of the unlucky "responders": https://www.hsph.harvard.edu/nutritionsource/what-should-you...
Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @04:13PM (#23586859)
yeah. people don’t really understand that it’s not the cholesterol in food that necessarily matters - most of the cholesterol that circulates in your blood is actually produced by your liver.

also, there are different phenotypes when it comes to cholesterol. For some a LFHC diet does wonders, for others it’s a sure way to have problems down the line if you sustain it for long periods of time.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by raincom on Saturday June 20, 2020 @03:55PM (#23586693)
Re:Low carb diet leads to “clinical remission” in 3 cases of... by e40 on Saturday June 20, 2020 @03:57PM (#23586717)
High cholesterol does not cause CHD. My PCP doesn't even check it anymore.

There is a lot of money behind the drugs that require us to believe this.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by heavyset_go on Saturday June 20, 2020 @04:28PM (#23586995)
Show me the clinical evidence that supports your claims, because there are tomes of evidence that suggest the exact opposite.

There's a lot of money behind that "One Weird Trick That Doctors Hate and Your Stomach Will Love", too, but not a lot of evidence.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by huffmsa on Saturday June 20, 2020 @03:54PM (#23586681)
Had you had it checked before starting the diet?
Re:Low carb diet leads to “clinical remission” in 3 cases of... by dragonfax on Saturday June 20, 2020 @03:56PM (#23586704)
The Ketoers say this isn't a problem. That cholestorol is misunderstood, and high values are only bad if you eat high carbs. If your low carb then the high value is actually normal and healthy.

But YMMV

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @04:18PM (#23586912)
sorry but this is bs and straight dangerous. cholesterol itself is not dangerous but the proteins that carry it in the blood stream are. That’s why LDL is bad and HDL is good (supposedly 2 types of cholesterol- but they’re not they’re two types of proteins). The LDL are the smaller ones that actually end up, in time, piercing the lumen (blood vessel wall) and causing inflammation. this is how your arteries narrow and this is how you eventually end up with heart disease.

so the LDL particles (by count not volume) are bad and whoever tells you otherwise is full of crap

Re:Low carb diet leads to “clinical remission” in 3 cases of... by virtuallynathan on Saturday June 20, 2020 @05:17PM (#23587380)
“piercing the lumen” is a drastic over-simplification. We don’t know how much LDL is in a healthy lumen (the small amount of research that exists suggests its greater than the serum concentration). Much of it gets there via active transport mechanisms (transcytosis).

Also, why would an endogenously produced protein end up killing you? Seems like evolution run-amok.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by rantwasp on Saturday June 20, 2020 @06:32PM (#23587974)
haha. it’s amazing how complicated even the simplest forms of organic life are. things do go wrong all the time and there are complex mechanisms to balance things out. that being said systematic imbalance or just “wear and tear” eventually win.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by heavyset_go on Saturday June 20, 2020 @04:18PM (#23586913)
It's anecdotal evidence, but I know of a fairly young person who is now prescribed statins after overeating animal fat for their keto diet.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by barrenko on Saturday June 20, 2020 @04:49PM (#23587175)
Statins are poison.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by jadell on Saturday June 20, 2020 @04:07PM (#23586814)
I'm glad you found a diet that works for you, makes you feel healthier, and has improved you QoL.

But it's not a panacea, and it's certainly not a cure for type 1 diabetes.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by NotHereNotThere on Saturday June 20, 2020 @04:11PM (#23586840)
He never mentioned it being a cure to T1D..
Re:Low carb diet leads to “clinical remission” in 3 cases of... by jadell on Saturday June 20, 2020 @04:15PM (#23586883)
The response is to an article about low carb diets sending diabetes patients into "remission". It's hard not to make the connection.
Re:Low carb diet leads to “clinical remission” in 3 cases of... by NotHereNotThere on Saturday June 20, 2020 @04:40PM (#23587105)
Well.. I don't actually think the article claims a 'cure' either.

If I get cancer, have treatment for it and am now in remission, who would think these doctors 'cured' cancer? Everyone would understand _my specific instance_ of cancer is reduced to being not a concern anymore.

Being in remission just means a greatly reduced or almost inexistent dependency on insulin.

I'm not saying the conclusions of the article are correct either (low sample size, short period of time), but it's a far cry from claiming 'LCHF cures T1D'

Re:Low carb diet leads to “clinical remission” in 3 cases of... by capkutay on Saturday June 20, 2020 @04:05PM (#23586792)
If your definition of 'low-carb diet' includes red meat, cheese, and butter then high cholesterol shouldn't surprise you at all.

People should really look at minimizing their intake of animal fats. Both for ethical and health reasons.

Re:Low carb diet leads to “clinical remission” in 3 cases of... by halfcat on Saturday June 20, 2020 @04:28PM (#23587002)
> People should really look at minimizing their intake of animal fats. Both for ethical and health reasons.

I’m all for the ethical angle. Factory farming is horrific.

But why health? I certainly haven’t read every study out there, but I’ve read a lot of studies, and what I can’t find is causal evidence of negative health effects of animal products in the absence of sugar. Do you know of any studies I can read?