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Re:Hundreds of thousands in L.A. may have been infected with... by strangeloops85 on Monday April 20, 2020 @05:44PM (#22928964)
I think NYC almost certainly has much large prevalence than LA given hospitalization data alone.

One factor could be the nature of transmission. Regions where transmission occurs with high viral loads entering at the point of infection (for example, hospital-acquired infections) could see more severe disease progression. You would therefore expect a high hospitalization rate relative to prevalence. It's possible in other regions, including CA, hospitalization rate as a function of prevalence is lower because acquisition is largely at lower viral loads resulting in less rapid and severe disease progression. This is, of course, a hypothesis and very likely not correct. Time will tell.

Other important factors include age distribution of infection, as well as weather conditions and prevalence of pre-existing conditions.

Re:Hundreds of thousands in L.A. may have been infected with... by Scipio_Afri on Monday April 20, 2020 @05:54PM (#22929083)
I also suspect and absolutely think a large portion of the reason there is a decrease in hospitalizations is due to mitigation efforts decreasing the initial viral load. That is absolutely borne out of all evidence we know thus far for this virus and is also in line for what we know to be true about other viruses.
Re:Hundreds of thousands in L.A. may have been infected with... by strangeloops85 on Monday April 20, 2020 @06:40PM (#22929611)
Excellent point!
Re:Hundreds of thousands in L.A. may have been infected with... by tempsy on Monday April 20, 2020 @05:48PM (#22929011)
Yes agree NYC will have much higher prevalence but it has 17x the deaths - if fatality rate is similar then it would be like 50%+ of New Yorkers have contracted Covid. Just a little hard to believe.
Re:Hundreds of thousands in L.A. may have been infected with... by hilbertseries on Monday April 20, 2020 @05:50PM (#22929044)
5.6m people ride the New York subway everyday.
Re:Hundreds of thousands in L.A. may have been infected with... by catlas3r on Monday April 20, 2020 @08:00PM (#22930336)
Actually, no they don't. There are 5.6m rides per day. The average trip contains at least two rides: there, and back again. Many trips contain substantially more than two legs, and many people take more than one trip per day.

I can't tell you how many people ride the subway every day, but it's certainly less than half of the number of rides per day.

Re:Hundreds of thousands in L.A. may have been infected with... by throwaway3563 on Monday April 20, 2020 @08:08PM (#22930392)
Number of rides is actually more relevant in this context than number of distinct riders. Each trip involves a new set of people next to you in the train car and a new chance of getting infected.
Re:Hundreds of thousands in L.A. may have been infected with... by catlas3r on Monday April 20, 2020 @08:21PM (#22930487)
The number of rides is useless in estimating the percentage of the population with high risk for exposure if you don't also have the proportion of the population exposed to that risk.
Re:Hundreds of thousands in L.A. may have been infected with... by tempsy on Monday April 20, 2020 @05:56PM (#22929115)
There’s a decreasing number of positive test cases each day in NYC too though. At highest point was 50% and now under 30% or so. I’m not sure if those tested get the antibody test as well but it implies a larger percentage of symptomatic people are testing negative in nyc.
Re:Hundreds of thousands in L.A. may have been infected with... by asdf21 on Monday April 20, 2020 @06:24PM (#22929453)
Almost no one gets an antibody test yet, unless it's some special controlled study.
Re:Hundreds of thousands in L.A. may have been infected with... by trexmix on Tuesday April 21, 2020 @09:00PM (#22940981)
Re:Hundreds of thousands in L.A. may have been infected with... by timr on Monday April 20, 2020 @05:56PM (#22929112)
What makes it hard to believe, exactly?

One way to explain the hospital surge in NYC is that a small percentage of people have had a highly fatal disease. Another plausible explanation is that a much larger number of people have had a less-fatal disease.

To date, we've had very poor estimates for fatality rates and prevalence. It wouldn't be shocking at all to find out that we're off by a factor of 10-, 20-, or even 50-fold.

Re:Hundreds of thousands in L.A. may have been infected with... by eloff on Monday April 20, 2020 @06:33PM (#22929539)
Typically a sufficiently infectious disease tops out around 50-80% (don't have a source, just what people, like Angela Merkel have been saying). So this implies NYC is already off the high end of that. Hard to believe.
Re:Hundreds of thousands in L.A. may have been infected with... by DeonPenny on Tuesday April 21, 2020 @04:58AM (#22933214)
How is that hard to believe that incredibly obvious with the dropping hospitalization rates
Re:Hundreds of thousands in L.A. may have been infected with... by timr on Monday April 20, 2020 @07:02PM (#22929808)
NYC has had ~141,000 infections confirmed. If the high end of this study held for NYC (50x), then the true infection count would be around 7M.

That isn't impossible at all, given that the population of NYC is around 8.8M people. It would mean that the city is approaching herd immunity.

(I don't personally think the ratio will be as high in NYC as in LA, but that's just a hunch based on the higher testing rate.)

Re:Hundreds of thousands in L.A. may have been infected with... by eloff on Monday April 20, 2020 @07:15PM (#22929935)
That's basically the top end of the estimate of what is theoretically possible without a lockdown and infinite time. I just don't buy that it is already maxed out like that.
Re:Hundreds of thousands in L.A. may have been infected with... by timr on Monday April 20, 2020 @11:16PM (#22931481)
It's the top end estimate from the study. Even if you take the low-end estimate (~30x), there would be 4.2M cases, which is still ~50% of the New York population.

Basically, you're just saying that you don't want to believe what they're saying, therefore it's hard to believe. But there's nothing illogical or impossible about it in the slightest.

Re:Hundreds of thousands in L.A. may have been infected with... by eloff on Tuesday April 21, 2020 @01:01AM (#22932096)
Even 50% is hard to believe. Illogical or impossible, no. Improbable, I think so.
Re:Hundreds of thousands in L.A. may have been infected with... by DeonPenny on Tuesday April 21, 2020 @04:59AM (#22933222)
You keep making assumption. You have to concluded the lock-down did nothing, has done nothing, and hasn't prevented any infections. You can make assumption because the numbers don't align to what you assumed they'd be.
Re:Hundreds of thousands in L.A. may have been infected with... by vkou on Monday April 20, 2020 @11:58PM (#22931709)
If what you're saying is true, then the NYC death rate will drop to zero in three weeks.

I am willing to bet the farm that it won't.

Re:Hundreds of thousands in L.A. may have been infected with... by DeonPenny on Tuesday April 21, 2020 @05:00AM (#22933230)
That seems weird since all data points to that being whats happening.
Re:Hundreds of thousands in L.A. may have been infected with... by DanBC on Tuesday April 21, 2020 @05:02AM (#22933240)
What data?
Re:Hundreds of thousands in L.A. may have been infected with... by eloff on Tuesday April 21, 2020 @01:01AM (#22932099)
Yeah, likewise.