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Re:Hydroxychloroquine Probably Isn’t the Answer by jacquesm on Sunday April 05, 2020 @10:23AM (#22785688)
"If there was any effect of this drug on COVID-19, it was minimal. Hydroxychloroquine, whose toxicity is far lower, may be safer than chloroquine. But that doesn't matter if the drugs are ineffective."

What's political about that?

The whole idea that if there were a simple and cheap cure that it would be politicized to the point where it won't see widespread application is ridiculous.

Re:Hydroxychloroquine Probably Isn’t the Answer by pbreit on Sunday April 05, 2020 @03:20PM (#22787806)
It's very clear that the resistance to these drugs is an intense case of Trump Derangement Syndrome.

There's an almost perfect correlation between reaction to these drugs and Trump support.

Re:Hydroxychloroquine Probably Isn’t the Answer by xtof on Sunday April 05, 2020 @03:49PM (#22788061)
It's resistance to people who are clearly out of their lane. He is not a medical doctor, yet he's recommending people take it. It's unremarkable that he's incompetent to give this advice, because most people are incompetent to give such advice. I am incompetent to give such advice. What is remarkable is he clearly thinks he's competent to give such advice, and that it's appropriate for him to give it without any qualification whatsoever. https://mobile.twitter.com/atrupar/status/124655621931107942...
Re:Hydroxychloroquine Probably Isn’t the Answer by miked85 on Sunday April 05, 2020 @03:55PM (#22788114)
A fair amount of doctors tend to believe it is promising [1]. If I was in the hospital, of course I would want to take it regardless of how anecdotal the evidence is.

[1] https://www.washingtontimes.com/news/2020/apr/2/hydroxychlor...

Re:Hydroxychloroquine Probably Isn’t the Answer by justin66 on Sunday April 05, 2020 @04:43PM (#22788554)
> A fair amount of doctors tend to believe it is promising

There are a couple of red flags about that article. No peer-reviewed (or otherwise) papers are mentioned and no clinical trials are discussed. The article does not even attempt to evaluate the truth of whether it's an effective therapy.

Even judged on its own terms, the article is a weak. After looking at that survey they're flogging, it'd be pretty interesting to hear from Spanish doctors, since that's where most of the enthusiasm seems to be coming from, but they don't even attempt to talk to anyone. Well... it's the Washington Times.

> of course I would want to take it

"Of course?" I hope you would at least consider the opinion of the physician treating you.

Re:Hydroxychloroquine Probably Isn’t the Answer by miked85 on Sunday April 05, 2020 @10:11PM (#22790358)
> "Of course?" I hope you would at least consider the opinion of the physician treating you.

Sure. But if I was dying, "of course" I would want to try something with even anecdotal evidence of efficacy.

Re:Hydroxychloroquine Probably Isn’t the Answer by pbreit on Monday April 06, 2020 @01:34AM (#22791140)
Re:Hydroxychloroquine Probably Isn’t the Answer by pbreit on Monday April 06, 2020 @01:34AM (#22791136)
Trump mentioning a drug in a press conference is now "giving [medical] advice"? Please.
Re:Hydroxychloroquine Probably Isn’t the Answer by shripadk on Sunday April 05, 2020 @10:27AM (#22785714)
> What's political about that?

Then why does the title say that Hydroxychloroquine "probably" isn't the answer? It either works or it doesn't. If the drugs are ineffective just say so. Why beat around the bush with a "probably"?

Re:Hydroxychloroquine Probably Isn’t the Answer by jacquesm on Sunday April 05, 2020 @10:28AM (#22785723)
Probably as in 'not yet 100% sure'. As a measure of probability based on available evidence.
Re:Hydroxychloroquine Probably Isn’t the Answer by Natsu on Sunday April 05, 2020 @02:47PM (#22787522)
To me, the headline reads like it's saying "this probably won't work" rather than "we don't yet have enough evidence to say that this works." If I had to headline this article, I probably would have written something like "Hydroxychloroquine data still inconclusive, don't get your hopes up yet" to better convey the meaning.

From reading it, what the article actually supports is that we have seen two trials that are inconclusive. This is the meat of it in my view -

==

A French study of HCQ suggested that it had was effective in decreasing the viral load from nasal secretions. When azithromycin was added the magnitude of the effect was larger.

[...]

And a Chinese study of 30 patients doesn't prove that HCQ worked. Or that it doesn't. But the two groups, control and treated, showed no difference in the amount of virus in the throat on day seven, the length of time for the fever to go away. There was an apparent difference in the progression of the infection (determined by x-ray), in the two groups but this means little since 5/15 treated patients got worse vs. 7/15 in the control group. This effect could easily be by chance and nothing to do to the drug. Furthermore, this trial did not include azithromycin, so it cannot be compared to the French trial.