In 2014, incidents where at least one driver had a detectable amount of alcohol in their system accounted for 36% of traffic fatalities in the US. Even if you exclude those fatalities entirely, driving is still 70x more dangerous.
Now of course you can claim that you're just a better driver than the average person (like 93% of Americans do [3]), but no matter how good of a driver you are, I doubt if it would come anywhere close to making up for a 70x difference.
[1] http://faculty.wcas.northwestern.edu/~ipsavage/436-appendix....
[2] https://crashstats.nhtsa.dot.gov/Api/Public/Publication/8122...
Also, these statistics are about commercial flights on perfect routes v.s. all the drivers on all kind of roads. I looked a bit and it seems like the accidents on the highways are significantly less likely and the deaths rete per crash is lower too.
A fairer comparison would be small chartered jets v.s. Uber, commercial coach services v.s. commercial flights on similar routes and so on.
I don't know even if it's a meaningful comparison anyway, on long journeys or on short ones they do not overlap.
When you are in an aircraft, the biggest risk is takeoff and landing. After that, assuming a well maintained aircraft, most of the risk is mitigated by the fact that your flight deck has thousands of hours of experience and most major components of the aircraft have some level of redundancy. The crew are not even allowed to eat the same meal to rule out food poisoning.
How so? Is flying still safer than driving a well-maintained car and observer safety best practices? Or is it safer in regards to grand scheme of things and you might be one of those drivers that be drunk driving? Well, you can not drink and drive, it's not really random from a personal perspective.