The clip itself is from a TV show that, from what I can determine, was originally broadcast on the 22 of February 2009. Know Your Meme dates the clip’s use as a meme to as early as May 2011¹. If you have an earlier reference, I’m sure they would appreciate being informed, if you can give a link to to it.

1. https://knowyourmeme.com/memes/mind-blown