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Re:Psilocybin for major depression granted Breakthrough Ther... by throwaway1126 on Tuesday November 26, 2019 @11:18AM (#21639594)
I won't pretend to understand the neuroscience, but consider: Today's antidepressants work by affecting your serotonin. Another serotonin-affecting drug comes along, and it's assumed to be "placebo"?

Personally I tried it. A very low dose completely wipes out any depression or negative thought for weeks at a time. Way better than zoloft.

Re:Psilocybin for major depression granted Breakthrough Ther... by newnewpdro on Tuesday November 26, 2019 @01:14PM (#21640976)
Agreed.

I'm surprised by the focus on large psychedelic trip doses and placebos in this thread. It's basically two opposing extremes.

I too have observed incredible effects of taking small below-threshold doses of psilocybin, with absolutely no negative effect whatsoever. It's tempting to incorporate half a stem into my regular morning routine like a vitamin.