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Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by caymanjim on Wednesday August 21, 2019 @06:34PM (#20762645)
I've been a long-time smoker, and at least for me, nicotine alone does absolutely nothing to alleviate cravings. Gum, patches, lozenges, vaping, etc. do zero to alleviate my craving for a cigarette. I'm not discounting that nicotine is addictive (I'm in no position to say), but there's got to be something else in tobacco that is part of the addiction.
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by 01100011 on Wednesday August 21, 2019 @06:46PM (#20762743)
Nicotine only makes me sick. I've tried gums, vapes, and nicotine salt pouches. I smoke a tobacco pipe when I want to relax.

There are MAOIs in tobacco smoke. I'm not sure that's what makes me feel calm though.

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by Jarwain on Wednesday August 21, 2019 @07:26PM (#20763021)
It could be the interaction between the MAOIs and the nicotine. Or more accurately, the MAOIs altering how your body handles nicotine.
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by caymanjim on Wednesday August 21, 2019 @07:59PM (#20763264)
There are sibling comments discussing MAOIs, and I've heard about them before in relation to smoking. It makes me wonder if MAOIs alone would be better for smoking cessation. I don't think I'm all that addicted to the nicotine itself. There are plenty of other supposedly-addictive stimulants that I can take or leave at will and with no feelings of withdrawal, and nicotine does nothing to alleviate cigarette withdrawal for me, so I'm not sure it's even a necessary component. There are some NIH studies about MAOIs and smoking, but I'm not going to link them because I find them incomprehensibly dense.
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by tonyarkles on Wednesday August 21, 2019 @08:30PM (#20763461)
I don’t remember what family of antidepressant Bupropion (Wellbutrin/Zyban) is, but it helped me immensely the first time I quit. I literally just woke up one day (a few days before my target quit date) and had no craving at all.

It also made me a little bit manic, and weaning off it sucked, but it worked well in general.

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by enraged_camel on Wednesday August 21, 2019 @10:29PM (#20764083)
Addiction has two components: chemical(i.e. nicotine) and psychological (i.e. the habit of the ritual).

My mom recently switched to e-cigarettes, and she said that she still occasionally gets the urge to smoke a real cigarette. But she said the urge is a lot weaker than when she used to go prolonged periods without smoking cigarettes, such as after a long plane ride.

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by hnzix on Thursday August 22, 2019 @02:24AM (#20765201)
Have you tried vaping using those e-cigs that look realistic, have a light up tip, and deliver a reasonable throat hit?

For me the addiction was partly psychological around the form factor. Using "light sabre" style vapes didn't work. However I was able to wean myself off smokes using realistic e-cigs (which I also eventually quit).

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by caymanjim on Thursday August 22, 2019 @02:35AM (#20765270)
They do nothing for me. They're also cheaply made and don't work well or consistently (and I've tried many brands).
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by Clubber on Thursday August 22, 2019 @08:29AM (#20767274)
The only thing that got me to quit smoking is the Juul. I tried everything else, but with the Juul, I just quit without having to consciously discipline myself 20 times a day. The gum was close though, but it took too long to kill the craving, so I'd end up chewing it constantly for it to work.

I've been smoking for a little over 20 years (since a teenager). Good luck.

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by topmonk on Wednesday August 21, 2019 @10:57PM (#20764248)
Have you ever tried Swedish Snus? It's supposedly healthier than smoking, and no need to spit like chewing tobacco.

If you try it. make sure you get fresh stuff before you pass judgment, because it ferments inside the package if left out for too long.

Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by haimez on Thursday August 22, 2019 @12:53AM (#20764747)
That’s how you get mouth cancer.
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by topmonk on Thursday August 22, 2019 @01:43AM (#20765007)
It's still considered the safest form of tobacco out there, and the increased risk of mouth cancer is quite small to non existent.

https://www.nytimes.com/2014/11/30/business/studying-snus-a-...

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Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by hnzix on Thursday August 22, 2019 @02:27AM (#20765220)
Telling addicts they "just need more willpower" is condescending and worthless advice.
Re:Acute Effects of Electronic Cigarette Aerosol Inhalation ... by gfosco on Thursday August 22, 2019 @02:37AM (#20765278)
We're talking about cigarettes here, not heroin. It's the only advice that matters.