Another major design constraint difference between "unmanned fighter" and "cruise missile" would be the deployment and reusability goals. Cruise missiles tend to need to fit in launch tubes or under wings, while presumably an unmanned fighter would not be so constrained (and thus be able to use larger wings). And while cruise missiles are very single use, the sensors on an unmanned fighter may make it too expensive to discard that way.
If we get real self driving cars how long till someone figures what you need to plaster on a tree to fool ML into crashing a car :) now imagine full nation state behind such effort. The risk of not having human in the loop is just too great.
You also just can’t do anything limited. I mean you can have even now fighter jet just kill anything it finds that does not transmit id, good in war maybe not so good at other times. Aegis is old tech and it is automated to kill anything that looks like a missile in full auto mode.
Iron dome probably same thing, engages and fires on full auto. Now imagine you hook it up to some automated 155mm battery, the moment missile get painted, it would start counter battery, I am guessing the round would land in Gaza before the rocket hits Israel. Now how many people would be ok with this is another question.
I mean, the benefits of a pilotless fighter jet are pretty significant: more maneuverable, faster, easier to design, and probably cheaper. I'm especially curious about fighter pilots' opinions about this.