I don't know what sort of confidence level you'd need to have in your defence systems to even start thinking of actually using nuclear weapons against another superpower - the risk is just too great.
They are terrifying against a state without a "nuclear umbrella". A few of these sneaky nukes could take out any ability to strike back conventionally. (Thinking of Sweden. Not that it longer could strike back anyway since about 1992.)
Or just send some hackers to cause as much chaos as they can with rewards instead of consequences.
Imagine the impact of deleting all financial records at a big bank.
As the crisis management consultant for trading companies, I can say what the impact will be -- about two weeks of sleepless nights and endless phone calls for the likes of me, grabbing all the data they can find from old backups, other counterparties, clearing agencies, and other guys and girls from the banking tech mafia, and plugging it back to the databases while the executives make their best poker faces and try to convince everybody that everything is all right.
Stuff like that (maybe with less scale, but still quite a lot of damage) happens occasionally... by accident, and thankfully stays unknown for the general public.
However, this might not be the case, as said superpowers can just decide to avoid nuclear confrontation (because of immediate counterstrike) and still fight conventionally — just like chemical weapons weren’t used on large scale in WW2, compared to WW1.