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A comment on Gene Therapy Was Hailed as a Revolution – Then Came the Bill. Parent comment

Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by codeulike on Monday April 08, 2019 @04:57AM (#19603401)
CRISPR's not that hard, this guy did it in his garage. Delivering it to cells is a bit harder, but not that hard unless you're talking brain cells, then the blood-brain barrier causes trouble.

https://www.theguardian.com/science/2017/dec/24/josiah-zayne...

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Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by refurb on Monday April 08, 2019 @10:46AM (#19605679)
Delivering it to cells is a bit harder

That's a bit of an understatement. The difference between doing CRISPR on a cell and a petri dish and doing it in a human is huge. That's why no one has done it yet.

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Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by dekhn on Monday April 08, 2019 @08:24AM (#19604520)
anybody with a decent level of biochemical knowledge can do these things in a garage (I built a biolab in my garage and work at a lab that does CRISPR). However, the person you cited is clueless and is just kind of injecting things into his body without any really thought to efficacy or safety.

There is a big difference between injecting reagents into a single human, and doing actual medicine.

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Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by Palptine on Monday April 08, 2019 @08:40AM (#19604628)
Tell that to the guy that tried to create HIV resistance babies in China. He had a decent lab yet both babies he created didn't have ccr5 hit: the crispr missed target.
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Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by folli on Monday April 08, 2019 @07:46AM (#19604263)
CRISPR is unrelated to Zolgensma, which uses an Adeno-associated virus to deliver a functioning version of the SMN1 gene.
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Re:Gene Therapy Was Hailed as a Revolution – Then Came the Bill by codeulike on Monday April 08, 2019 @09:17AM (#19604870)
I know. I was giving an example of modern biotech
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