Chrome doesn't have this. You cannot run tabs in different contexts in Chrome side by side.

Both additional profiles and incognito browsing open a different window, with its own settings.

The Chrome additional profile feature has also become a lot more confusing and less useful with the auto-sign-in-change debacle, alas.

Which may actually be what pushes me to FF. Not out of spite, just that I was counting on Chrome profiles for this purpose, but they've gotten a lot harder for me to use for that (and were never as good as FF's multi-container thing, it sounds like).

I use SessionBox ext in chrome to achieve this.

Exactly! unless they make different seed for each WebGL random (which used in fingerprinting) I don't see the point. Plus, they have your IP (or your VPN's), so at most you make your profile less specific, but never "isolated".