Tantalizing but preliminary evidence of a “brain microbiome”

Re:Tantalizing but preliminary evidence of a “brain microbiome” by empath75 on Tuesday November 13, 2018 @07:03AM (#18440345)

It would be interesting to find out that a lot of modern psychological diseases might be caused by excessive antibiotic use disrupting the brain microbiome.

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Re:Tantalizing but preliminary evidence of a “brain microbiome” by b_tterc_p on Tuesday November 13, 2018 @08:18AM (#18440693)

There is evidence to suggest antibiotics increase risk of anxiety and depression.

https://www.ncbi.nlm.nih.gov/pubmed/26580313

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Re:Tantalizing but preliminary evidence of a “brain microbiome” by tgb on Tuesday November 13, 2018 @07:17AM (#18440385)

Can antibiotics pass the blood brain barrier?

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Re:Tantalizing but preliminary evidence of a “brain microbiome” by blevin on Tuesday November 13, 2018 @09:18AM (#18441073)

Some do, including penicillin:

“Antibiotics that cross the BBB tend to have certain physical characteristics including: small molecular size, being lipophilic, binding to fatty molecules on cell membranes, low plasma protein binding and other specialized characteristics“

http://lymemd.blogspot.com/2013/03/blood-brain-barrier.html?...

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Re:Tantalizing but preliminary evidence of a “brain microbiome” by titzer on Tuesday November 13, 2018 @07:05AM (#18440352)

Antibiotics can certainly cause problems in the gut microbiome, but let's not jump to conclusions about the brain just yet.

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