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Re:Tantalizing but preliminary evidence of a “brain microbiome” by tgb on Tuesday November 13, 2018 @07:17AM (#18440385)
Can antibiotics pass the blood brain barrier?
Re:Tantalizing but preliminary evidence of a “brain microbiome” by blevin on Tuesday November 13, 2018 @09:18AM (#18441073)
Some do, including penicillin:

“Antibiotics that cross the BBB tend to have certain physical characteristics including: small molecular size, being lipophilic, binding to fatty molecules on cell membranes, low plasma protein binding and other specialized characteristics“

http://lymemd.blogspot.com/2013/03/blood-brain-barrier.html?...