There's a much simpler reason: the US is unbelievably large compared to European countries. The US equivalent to a London-Rome trip would be Washington, DC-Miami. Another example I give is that I used to live in Urbana-Champaign, which is "near" Chicago, which is roughly commensurate to saying that Paris is "near" Brussels.
And of course, the sheer size of the US also includes a massive diversity of climates and environments. The Florida Keys, North Carolina's Outer Banks, the Great Lakes, badlands in the Dakotas, Yellowstone, the Shenandoah Valley, Maine wilderness, Utah's canyons, Nevada's salt flats, San Diego--all of these places are completely different from one another. Not to mention we have our own Caribbean islands (US Virgin Islands, Puerto Rico), subarctic wilderness (northern Alaska), and Pacific paradises (Hawaii, American Samoa, Guam, Northern Marianas).
There might be a minor distinction to be made between having a no interest in other cultures and having £1500 lying around to fly to London.
1500? Easily doable for 500/600 return with some planning.
I get those values when searching MIA-London in Google flights, doable with other cities as well
However, is it perhaps possible that the precise numbers might not be particularly relevant to the point? It's still at least an order of magnitude more than the cheap flight, for two major destination cities about as far apart and Detroit and Dallas.
For example, from St. Louis, the cheapest round trip is in the ~$900 USD range.
Cancun has always been a popular destination.
Its $60 for EWR-ATL and I didn't even look hard. $260 EWR-SFO and that's a 5 hour flight.
https://www.reddit.com/r/MapPorn/comments/8fscnh/european_st...
International from/to the US is pretty much the same as everyone else in the world pays. This is based on my experience paying for and flying to 32 countries, many more than once.
My understanding about why Amercians don't fly international is the same as the UK used to be - not many even have a passport, and even less have an interest in cultures other than their own. For these last two comments I have no data, only hearsay.