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Re:Dying Organs Restored to Life in Novel Experiments by Engineering-MD on Monday July 16, 2018 @07:17AM (#17540350)
In clinical trials, pure placebos are very rarely used (only in mild conditions or where no treatment exists). Commonly novel therapies are compared against the current treatment of choice.
Re:Dying Organs Restored to Life in Novel Experiments by michaelscott on Monday July 16, 2018 @07:54AM (#17540541)
I was about to ask how ethical it could be to give a pure placebo in cases as serious as heart failure, when simply telling the patient (or the patient's family) that they received some other more conventional procedure should produce similar results.
Re:Dying Organs Restored to Life in Novel Experiments by nine_k on Monday July 16, 2018 @08:54AM (#17540900)
I think this is never done. I suppose both groups receive two therapies, one of them being the best available therapy for the condition, and the other either the new therapy, or a placebo.

This requires new and old therapies to be compatible, though.

Re:Dying Organs Restored to Life in Novel Experiments by ceejayoz on Monday July 16, 2018 @10:22AM (#17541434)
Studies will also be suspended if it becomes clear that one treatment is so obviously better as to be unethical to continue with the other.