That’s one point I have personally experienced. I’ve faced the reality of 30-31 migraines per 31 days a month. Luckily medical treatment is helping cut that number back significantly (though every day is a careful balance). But those medical treatments have been around less than 10 years. There’s even a class of headache, cluster headaches, which are also known as suicide headaches. Not every chronic pain can be dialed back.