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Re:Microsoft disables Spectre mitigations as Intel’s patches... by mehrdadn on Monday January 29, 2018 @04:52AM (#16256507)
> Windows executables are opened with mandatory exclusive locking. So you can't overwrite a program or its DLLs while any instances of it are running.

This is not always correct; see: https://news.ycombinator.com/item?id=16256483

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