Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by arthurpaul on Thursday January 25, 2018 @03:16PM
(#16234200)
https://www.ncbi.nlm.nih.gov/pubmed/26690210 - doses of 1885, 2802 and 6235 IU per day are required for normal weight, overweight and obese individuals respectively to achieve natural 25(OH)D concentrations (defined as 58 to 171 nmol/L)
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by nhylated on Wednesday January 24, 2018 @08:13PM
(#16227952)
I think you missed the link to the discussion in your comment.
Would taking 10x the RDA of Vitamin D daily have any side effects? (overdose?)
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by qwerty456127 on Wednesday January 24, 2018 @08:31PM
(#16228054)
Sorry. I've updated the comment and added the link. As far as I understand taking 10x the RDA won't have side effects because that's not an overdose, that's the correct dose and the RDA is a mistake.
I haven't tried this myself yet though. I am taking 1000 IU now (and it makes a difference I can feel already as compared to taking nothing or 1 RDA) while waiting for the 10'000 IU pills to get delivered from eBay. I didn't knew I actually need this much before reading the paper by the link.
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by skosch on Wednesday January 24, 2018 @08:18PM
(#16227990)
Max "official" safe daily limit is 4000 IU currently, but the only studies I'm aware of where actual toxicity was reported started at something like 40,000 IU daily for months. Vitamin D is likely pretty safe.
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by AstralStorm on Thursday January 25, 2018 @07:46AM
(#16230434)
No, the estimated RDA based on EPIC series of studies is 3000 IU daily and it's suspected to be on the lower side due to old people being bit overrepresented. This based on all cause mortality, various European subjects. Intake estimated by direct multiple blood levels.
Vitamin D intake vs mortality followed a very shallow U curve (almost J) and minimum was between 2000 and 4000 IU.
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by qwerty456127 on Thursday January 25, 2018 @08:00AM
(#16230501)
So the RDAs are about just decreasing mortality rather than improving life/health, right?
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by qwerty456127 on Thursday January 25, 2018 @05:52AM
(#16230069)
I just wonder how does official data of this kind emerge if not based on any studies.
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by zappo2938 on Wednesday January 24, 2018 @07:42PM
(#16227772)
I love taking vitamin D before bed. It passes me right out.
Re:Acne Vulgaris: A Disease of Western Civilization (2002)
by skosch on Wednesday January 24, 2018 @08:20PM
(#16228004)
You must be an outlier; the consensus seems to be that it counteracts fatigue: https://www.gwern.net/zeo/Vitamin-D
I have also heard a rumor that recent studies suggest solid vitamin D pills are better than oil capsules. Would be nice if somebody knowing what particular study says this could share a link.