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A comment on Acne Vulgaris: A Disease of Western Civilization (2002). Parent comment

Re:Acne Vulgaris: A Disease of Western Civilization (2002) by skosch on Wednesday January 24, 2018 @08:18PM (#16227990)
Max "official" safe daily limit is 4000 IU currently, but the only studies I'm aware of where actual toxicity was reported started at something like 40,000 IU daily for months. Vitamin D is likely pretty safe.
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Re:Acne Vulgaris: A Disease of Western Civilization (2002) by AstralStorm on Thursday January 25, 2018 @07:46AM (#16230434)
No, the estimated RDA based on EPIC series of studies is 3000 IU daily and it's suspected to be on the lower side due to old people being bit overrepresented. This based on all cause mortality, various European subjects. Intake estimated by direct multiple blood levels.

Vitamin D intake vs mortality followed a very shallow U curve (almost J) and minimum was between 2000 and 4000 IU.

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Re:Acne Vulgaris: A Disease of Western Civilization (2002) by qwerty456127 on Thursday January 25, 2018 @08:00AM (#16230501)
So the RDAs are about just decreasing mortality rather than improving life/health, right?
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Re:Acne Vulgaris: A Disease of Western Civilization (2002) by qwerty456127 on Thursday January 25, 2018 @05:52AM (#16230069)
I just wonder how does official data of this kind emerge if not based on any studies.
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