News for hackers. Stuff that matters.
Re:Adderall Risks: Much More Than You Wanted to Know by astrange on Saturday December 30, 2017 @03:10AM (#16034361)
> There are occasional claims that magnesium or some other substance can help reverse Adderall tolerance.

I went to a particularly expensive Silicon Valley psychiatrist who did of course immediately put me on Adderall, but also put me on NAC supplements to "avoid tolerance". It's been okay, they're cheap, never bothered not taking them to experiment. I can confirm feeling better after eating foods with magnesium, mostly because they're good for you.

BTW, if you're on amphetamine+guanfacine you need to avoid all of caffeine, sugar, and alcohol. What a bummer.

Re:Adderall Risks: Much More Than You Wanted to Know by png_hero on Saturday December 30, 2017 @11:17AM (#16035840)
Hmmm, never heard of adding NAC. And do you supplement magnesium too?

Your talking about things I’ve never heard of before, this does sound advanced. Any other things on your stack?

Re:Adderall Risks: Much More Than You Wanted to Know by astrange on Saturday December 30, 2017 @01:48PM (#16036704)
Guanfacine (Tenex/Intinuv) is just a prescription you can get for ADHD hyperactivity. It complements stimulants really well but is hard to live with - you feel sedated, have no alcohol tolerance, and ramping off it takes a week or two.

> Any other things on your stack?

Like nootropics? Popular internet topic but a little goes a long way. Here's what I know:

- Vitamin D 1k-5k IU, fish oil, theanine: These all work great and everyone should try them.

- Magnesium: Too many different supplement formulations to trust one, and I read they give you copper deficiency - just eat spinach and you're good. Actually zinc is better to supplement, especially for men.

- Nootropic stacks like Qualia: Tried some, but pretty sure they're expensive caffeine pills.

- Every other nootropic: Bacopa helps long-term but makes ADHD worse short-term(!). No effect from anything else.

Re:Adderall Risks: Much More Than You Wanted to Know by fragsworth on Saturday December 30, 2017 @12:02PM (#16036086)
> Hmmm, never heard of adding NAC. And do you supplement magnesium too?

> Your talking about things I’ve never heard of before, this does sound advanced. Any other things on your stack?

The original article mentioned how society has determined it is "not okay for people with already-fine concentration to use it to become superhuman".

The way you talk about this, though. Being impressed about someone's "advanced stack" of drugs to maximize their potential. I get the impression you're using it to become superhuman.

I'm not sure if I am the only one with this reaction, but I feel like your attitude is kinda offensive and disgusting. How much money have you made by abusing drugs in our rat race?

Re:Adderall Risks: Much More Than You Wanted to Know by png_hero on Sunday December 31, 2017 @04:04AM (#16039921)
> I feel like your attitude is kinda offensive and disgusting. How much money have you made by abusing drugs in our rat race?

Yeah, I am kinda disgusted myself, but I am right on the cusp, and I am grasping at it. That last sprint. I’ve locked in 99.5%-tile wealth, but the next month to six will determine if I can get into 99.9%-tile, where the true game change is.

And I’m under no illusion, if I don’t bag this deal here for the 99.9%-tile (private aviation, super yacht and models) I’ll forever be stuck at 99.5%-tile (first class commercial, upper middle class lifestyle forever without having to work).

Just a little more... broke my way many times... just need this last bit...

Re:Adderall Risks: Much More Than You Wanted to Know by fragsworth on Tuesday January 02, 2018 @11:34PM (#16058429)
Fair enough
Re:Adderall Risks: Much More Than You Wanted to Know by sigotirandolas on Saturday December 30, 2017 @10:49AM (#16035720)
AFAIK the best evidence is for NMDA antagonists reversing tolerance. In fact magnesium is a a NMDA antagonist, but it a very weak one. I have read about people using memantine or something more potent to reverse tolerance, but I would be very wary about using potent NMDA antagonists regularly given what we know about them.