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Re:Adderall Risks: Much More Than You Wanted to Know by sigotirandolas on Saturday December 30, 2017 @10:49AM (#16035720)
AFAIK the best evidence is for NMDA antagonists reversing tolerance. In fact magnesium is a a NMDA antagonist, but it a very weak one. I have read about people using memantine or something more potent to reverse tolerance, but I would be very wary about using potent NMDA antagonists regularly given what we know about them.

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