Kidneys: https://examine.com/nutrition/does-creatine-cause-kidney-pro...
Overall, it's a very safe and moderately effective supplement, particularly if you don't eat a lot of red meat. Just make sure to drink enough water.
I wouldn't say I've been depressed (a psychiatrist might disagree, I've been dx'ed with it in the past), but daily 5mg creatine and 2k IU vitamin D have made a remarkable difference in mood/energy for me this year.
A few months ago a young man (early 20's) came into a shop I sometimes hang out at. "What brought you to town?" "Recovery." He'd been in town for 3 weeks, and sober for 3 weeks and 1 day.
I asked him, "People usually know when their problems when substances started, when did it start for you?"
When he was in 3rd grade his teacher thought he was disruptive. They put him on some kind of medication for "ADHD". He told his parents in 9th grade that he was going to kill himself if they didn't take him off the pills. Soon after discontinuing his "ADHD" medications was when he started experimenting with self-medicating... Tobacco, alcohol, etc.
His latest bender was on alcohol & laughing gas (nitrous oxide [0], for the euphoria).
[0] https://en.wikipedia.org/wiki/Nitrous_oxide#Recreational_use
After a bit I told him, "I bet you're exhausted."
"YEAH!"
"Recovery" is good for getting people to feel like failures, so I thought it'd be helpful for putting a different 'frame' on his last 15 years. I told him that he doesn't actually have a substance abuse problem, he's just been exhausted this whole time, and didn't know what to do to help improve his energy levels. I gave a few suggestions for keeping his energy levels up.
Saw him three or four more times over the next 2-3 months, and he was doing much better. I saw him last 2 days before he returned to where he came from. I think he's got a chance this time.
I don't think that guy was able to get the coconut oil while at the recovery center. I think giving a more helpful context for viewing his history of addiction was much more helpful than the recommendation for coconut oil.
Another heavy drinker I know does fine while on "vacation", but "stress" in his every day life leads to excess drinking. I have no influence with this one, but I'd try to get him to eat more sweets when in stressful situations - juices/etc. I've heard an old treatment for alcohol withdrawal is to feed them lots of sugar. Here's a random NY Times article that says sugar helps reduce cortisol levels: https://well.blogs.nytimes.com/2015/04/23/sugar-as-a-stress-...
IMHO, sugar in juices and other foods is basically fine; starch is 100% glucose and is a greater contributor to excess weight. Lots of caveats with regards to the sugar issue...
> Depression has to be about something more than just beliefs; it has to be something fundamental to the nervous system.
Depression is frequently related to metabolic problems: people are exhausted because their mitochondria aren't putting out enough ATP to run their nervous system.
There are various interventions that can help. B-vitamins are important cofactors for burning sugar to make energy. T4 thyroid is activated by the liver to make T3, which is one factor that boosts the metabolism. If the liver is overworked (alcohol, drugs, hormonal imbalance, too much pufa, etc), it can have trouble activating adequate thyroid.
Emotional resiliency is a big factor here too. My friend was really just lonely before she met me. She's doing better now because she now has a 'vision' for her future (she originally 'lost her future' when she was expelled from high school, essentially for being depressed and self-medicating with drugs that are now being investigated for treating depression).