The main problem is that there just isn't data on how much these drugs degrade. The expiration date is based on some preliminary measurements and conservative guesstimates. Neither the FDA nor the drug companies really cares or wants to see these dates extended.
Re:The Myth of Drug Expiration Dates
by BurningFrog on Wednesday July 19, 2017 @12:40AM
(#14802017)
There probably is no data in part because there is no good way to use such data.
Re:The Myth of Drug Expiration Dates
by Lordarminius on Tuesday July 18, 2017 @06:21PM
(#14800507)
> Here's a startup idea:...
How feasible would that be for thousands of different drugs with hundreds of thousands of different formulations and chemical compositions and various storage factors ?
Develop an "indicator pill" that changes color at the same rate as an individual medication.
It would be in (or part of) the bottle with the other pills, and be customizable to react to humidity, temperature and time in the same way as the particular medication.