Re:Close-Up View of DNA Replication
by haskman on Tuesday June 20, 2017 @03:18AM
(#14592739)
That was amazing! Especially the machinery of the second part where the DNA strand is replicated backwards!
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Have a look at this lecture. It's really well explained, at a undergrad level, how the cell keeps the error rate low. Quite impressive, imo. https://youtu.be/DRBREvFL19g
That looks more error-prone, wonder if that copy has more mutations...
yes, e.g. [1], but there are specialized repair mechanisms that operate at the same time, so the 'final' error rate is much lower than the 'initial' rate.
[1]: http://www.nature.com/nature/journal/v518/n7540/abs/nature14...