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Re:'Tooth repair drug' may replace fillings by kalleboo on Monday January 09, 2017 @10:40PM (#13362370)
Most of Europe and Japan doesn't fluoridate their water and they don't have notably worse dental outcomes.

It really has to do with toothbrushing and diet. Water fluoridation is just a way to get to the people who refuse to brush their teeth.

Re:'Tooth repair drug' may replace fillings by stplsd on Monday January 09, 2017 @11:28PM (#13362565)
I think genetics have a part too. My grandmother was deported to Siberia (https://en.wikipedia.org/wiki/Soviet_deportations_from_Lithu...) for 20 years where they have 200 grams of bread a day at best and never brushed her teeth in her life and never had a tooth filling or missing tooth before her retirement, and I have half my teeth missing and I am only 30 years old. Fuck my life.
Re:'Tooth repair drug' may replace fillings by torinmr on Monday January 09, 2017 @11:52PM (#13362685)
Could that also be related to diet? I'm guessing your grandmother practically never ate sugar if she was living on 200 grams of bread a day.

I've also heard that early modern humans had fairly good teeth for their age despite the presumed lack of dental care, presumably also due to differences in their diet from us.

Re:'Tooth repair drug' may replace fillings by Cerium on Tuesday January 10, 2017 @01:27AM (#13363091)
Diet is super important. I used to drink orange juice every day. I got a cavity every 6 months. I have stopped drinking orange juice and have not had a cavity since.
Re:'Tooth repair drug' may replace fillings by filoeleven on Tuesday January 10, 2017 @01:48PM (#13367663)
I just heard a radio piece about how basically all humans had Hollywood smiles (where the teeth lined up perfectly) until the Industrial Revolution, when our jaws began to shrink and there was no longer enough room for all the teeth. I didn't get to hear the part where they discussed/hypothesized whether the changes were due to diet or environment or something else.
Re:'Tooth repair drug' may replace fillings by robbiep on Tuesday January 10, 2017 @03:50AM (#13363560)
So ¼ of your genetic material had a diet in which she never had a filling, and you on a different diet at age of 30 are missing many teeth, and you conclude that it's genetics?

Either some leap of logic or information is missing there or you're drawing the wrong conclusion from your data

Re:'Tooth repair drug' may replace fillings by cookiecaper on Tuesday January 10, 2017 @02:27AM (#13363298)
Yeah, there is undoubtedly a genetic side to it. My teeth decay rapidly -- as an under-two toddler, I had to undergo full anesthesia for a dental rehabilitation. Though neither my siblings nor my parents have very bad teeth, I've always been the exception (I guess I got just the right mutation). My pediatric dentist was always expressing astonishment at how quickly my teeth decay.

You know how dentists say "Hey, I can tell you drink a ton of soda, you need to stop"? I would get told this every time I'd go in for a cleaning, despite not drinking any soda and very little fruit juice/other sugary drinks for many years, 90%+ water only.

Fast forward 20-something years, and 2 of my daughters have had to undergo a dental rehab similar to mine at very young ages (though not quite as young as me), despite the stringent dental regimen my wife enforces to prevent this fate. There's no doubt that they got my bad teeth genes.

We're talking young kids here, ages 2-3 at the time of the operation (I was 18 mos. when I went down). They don't eat an inordinate amount of sugar, and as I stated above, my wife is very thorough with their dental hygiene. The water is fluoridated where we live. A lot of kids this age surely have much worse diets and much worse dental hygiene, but their teeth seem to be problem-free for many years.

Personally, I've had tons of fillings, 7-ish root canals, two teeth fully extracted because they were past saving, and several that badly need work and I'm not even 30 yet. Pretty much the only people living with worse teeth are opiate addicts.

I hope I win the lottery some day so I can get a mouth full of implants and be done with it. I hear the going rate for this is about $75,000.

A lot of people refuse to believe that genetics play any role, but that's absolutely not consistent with my experience, nor the opinion of most of the dentists I've had.

Re:'Tooth repair drug' may replace fillings by 52-6F-62 on Tuesday January 10, 2017 @10:16AM (#13365358)
I feel your pain on this one. I have a very similar problem.

My parents enforced our dental care and we went to the dentist regularly when I was young. Always once a year checkup and twice a year cleaning and still I had regular dental issues.

In the second grade I can recall being brought out of class to a tooth-care specialist the school brings in to teach kids who seem uncared-for to brush their teeth. I brushed twice a day.

When I was fifteen I remember being yelled at by my dentist about how I don't look after my teeth because I had "16" cavities (the dentist, mind you, in my later years I realized was actually a bit of a hack -- all of his work fell out of my mouth and left me in terrible pain).

Around this time the dentist put me on regular fluoride mouth washes -- I went home with a bottle of some god-awful "cherry" flavoured stuff. I _still_ had repeated problems.

Fast forward to the present -- I've had one infected wisdom tooth, one infected molar -- both had to be removed. I have one half-decayed wisdom tooth that will be extracted soon. This fall I've had to have 4 fillings (some of them were put off for a while mind you).

The next year I am pending a root canal and a crown, and my dentist also has informed me that (at age 30) I require jaw surgery or I face the possibility of regular migraines due to molar wear.

I floss, brush, and use mouth wash daily. I don't eat much sugar. My parents actually raised us on a lot of raw vegetables (my mother grew, and I was raised in rural southern Ontario in Canada -- something of a agriculture belt).

The only neglect would be that my parents could not afford braces when I was young.

There has got to be some genetic aspect. Or does Hacker News as a consensus believe in shit luck?

Re:'Tooth repair drug' may replace fillings by awfgylbcxhrey on Tuesday January 10, 2017 @01:19PM (#13367325)
Have you tried oral probiotics? Mind you, I have no reason to believe they'll help you, but at this point why not?

I think I first heard about them on HN. BLIS and K12 are the keywords, if I remember correctly.

Re:'Tooth repair drug' may replace fillings by throwaway00061 on Tuesday January 10, 2017 @04:17AM (#13363637)
You might want to pay Dr. Kim Kutsch a visit, or at least watch some of his webinars on YT. One of the things he recommends that could help you is ordinary bleach (sodium hypochlorite) heavily diluted to about 0.05% as an anti-microbial rinse.
Re:'Tooth repair drug' may replace fillings by grzm on Tuesday January 10, 2017 @04:36AM (#13363725)
Serious question. Why are you posting health-related advice from a throwaway account? If it's something you are recommending to others, posting from an established account would have much more weight.
Re:'Tooth repair drug' may replace fillings by throwaway00061 on Tuesday January 10, 2017 @04:47AM (#13363761)
I always use throwaway accounts and don't see why account karma should confer additional weight on anything I say.

Here's an article that reviews the literature on diluted bleach rinsing: http://www.rdhmag.com/articles/print/volume-35/issue-6/colum...

Re:'Tooth repair drug' may replace fillings by grzm on Tuesday January 10, 2017 @05:22AM (#13363880)
It doesn't have anything to do with karma. From a throwaway account, I have no basis to know who you are based on your other participation. HN is a community. Pseudonymity is fine, but anonymity is counter to the idea of community. I encourage you to establish yourself and be part of it.
Re:'Tooth repair drug' may replace fillings by cookiecaper on Tuesday January 10, 2017 @09:14PM (#13371210)
I know the other guy is giving you a hard time about the throwaway, but I do appreciate this. I'll watch some of his stuff, it looks interesting. Thanks for sharing.
Re:'Tooth repair drug' may replace fillings by shoover on Tuesday January 10, 2017 @08:18AM (#13364550)
I was astounded when Viktor Frankl reported the same thing in Man's Search For Meaning, observed in his time in a Nazi concentration camp. Your grandmother may well have superior dental genes, but there is something unique about that bread diet and camp/deportation life, too. Sorry to hear about your teeth.
Re:'Tooth repair drug' may replace fillings by adrianN on Tuesday January 10, 2017 @03:53AM (#13363571)
I think your oral microbiome is also important. I've heard about experimental treatments which replace the cavity causing bacteria with other strains that don't produce acids.
Re:'Tooth repair drug' may replace fillings by dethswatch on Wednesday January 11, 2017 @04:35PM (#13377687)
I read about that in the 90's- did anything become of it?
Re:'Tooth repair drug' may replace fillings by Johnythree on Tuesday January 10, 2017 @03:19AM (#13363481)
You are completely missing the point. Many areas already have sufficient fluoride.

It depends on the natural amount of fluorine in the water, if there's sufficient, then it's fine.

It's only in the relatively few areas where there is a deficiency that it's a problem.

And of course it also depends on diet.

Offsetting your claim are studies which show that where people exclusively drink rain water, there is a higher incidence of tooth decay.

Re:'Tooth repair drug' may replace fillings by kalleboo on Tuesday January 10, 2017 @06:25AM (#13364099)
The countries that don't fluoridate their water don't have minimum levels of fluoride required. Whereas they have maximum levels of fluoride contamination allowed.

I'm not one of those "fluoridation is a government plot to make everyone pliable" crazies. Just saying that it's far, far more important to BRUSH YOUR TEETH than to have a fluoridated water supply. Just seems to me like water fluoridation is just one of those crazy things Americans and places America has influenced do (such as using the customary measure system and circumcising their male children - sure if you dig deep enough you can justify it, but plenty of people get along just fine without it)

Re:'Tooth repair drug' may replace fillings by logfromblammo on Tuesday January 10, 2017 @02:10PM (#13367894)
The active component of tooth-brushing is removal of mutans-type bacterial colonies from the teeth.

Cavities do not form without cariogenic bacteria, provided with a food supply of simple sugars. If you have such bacteria, there are several ways to inhibit cavity-formation, such as by chemically hardening bioapatite with fluoride ions, or by re-mineralizing tooth enamel.

Communities would be better served by mutans eradication efforts, even though they could cost far more than the $1/person-year that fluoridation costs.

If I had the cash and political backing, I would put mutans-specific bacteriophages and tricalcium phosphate in a municipal water supply. I'd then subsidize dental office visits for persons in the affected area, such that anyone desiring fluoride treatments can get them at no additional charge, and offer gratis chlorhexidine/xylitol mouth rinse after every visit.

Kill the S. mutans; end cavities.

Re:'Tooth repair drug' may replace fillings by nkozyra on Tuesday January 10, 2017 @09:10AM (#13364788)
> The countries that don't fluoridate their water don't have minimum levels of fluoride required.

I think the point is that fluoridation is often unnecessary because of the natural amount of fluoride in the water.

Re:'Tooth repair drug' may replace fillings by dkersten on Tuesday January 10, 2017 @04:48AM (#13363765)
Water fluoridation is just a way to get to the people who refuse to brush their teeth.

That's not really true in and of itself -- fluoridation won't fix damage done by bad hygiene or diet. As someone else mentioned, genetics and other factors all play a part too.