The press liked to push the point that Insys made a fentanyl-based drug, but I believe it has far more to do with Insys's efforts at making marijuana-based drugs[1][2]. If marijuana became widely available, their efforts at marijuana-based prescription drugs would likely have a smaller market.

[1] http://syndros.com/

[2] Cannabidiol in development http://www.insysrx.com/products/in-development