Re:A theory on how insulin resistance, metabolic disease begin
by debacle on Thursday October 06, 2016 @09:45AM
(#12652371)
The most major finding, which appears to be this:
> The study found that fructose initiates a process that causes the liver to keep making glucose and raising blood glucose levels, even as insulin tries to keep glucose production in check.
Is not ground-breaking. It's how the liver metabolizes fructose. The liver can't respond to insulin because it needs to metabolize the fructose.
Re:A theory on how insulin resistance, metabolic disease begin
by echelon on Thursday October 06, 2016 @10:39AM
(#12652802)
I don't think that's fair. This is just a press publication; we'd need the actual paper to see what its specific claims are. Besides, very little in science is "ground-breaking" at first. Scientific progress happens most often through an accumulation of evidence over time.
(I took two semesters of immunology in my biochem undergrad--courses that I would have expected to cover this. I was never exposed to literature or material on this protein. I also haven't heard of it in the primary literature I do occasionally still read.)