That, or nix. Unfortunately the state of Darwin/OS X on nix has declined over the last year or so.

How has it declined?

It seems less people are involved or interested in solving the Darwin related issues. I have more issues getting things built and installed on OS X compared to a year ago. This mainly because it seems people aren't really interested in maintaining the OS X part of nixpkgs and some simply lack the resources to do so.

In the end it seems that this will get better if it can attract enough OS X users so that patches start rolling in but right now it's just a few people fighting that battle.

I don't like the lack of software diversity, but I see running Linux based containers on OSX as a viable solution to not having Nix support. Run nix in a container, create shimlinks so that everything is "transparent"