Recently a paper went by on how something like 90% of medical studies are not able to be replicated in follow-up studies. If you really understand science qua science (as opposed to science-as-religion-substitute), you should understand this isn't a minor interesting tidbit to be discarded, this is a dagger to the heart of the field. Other fields seem to be having similar problems.
I reiterate, science is still the best we've got and I don't anticipate a replacement. But the evidence strongly suggests that the quality of the real science being done is a lot lower than it may appear at first glance, or what some people would have you believe.
Actually, it's really amazing how many dangerously wrong ideas medicine has come up with over the years.
Science != popular reporting/understanding of science.
But the point about some of our understanding being wrong is right on the money.