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Re:Ketamine lifts depression via a byproduct of its metabolism by pierrec on Tuesday June 14, 2016 @12:21PM (#11903087)
"not to mention you're giving a _depressant_ to a depressed person"

Heh, these concepts are unrelated to the point that this statement could make a decent joke. As a rough example, it's on the level of "not to mention that you're installing a clock application on a computer that's already overclocked".

Re:Ketamine lifts depression via a byproduct of its metabolism by tgb on Tuesday June 14, 2016 @12:30PM (#11903169)
Love the example. In reminded of snopes' take on the "the car called Nova failed to sell in Mexico because 'no va' means 'it doesn't go' in Spanish" myth. Their example was of Americans not wanting to buy a car called "Notable" because it had no table.
Re:Ketamine lifts depression via a byproduct of its metabolism by 50CNT on Tuesday June 14, 2016 @12:51PM (#11903308)
Or was "not able".
Re:Ketamine lifts depression via a byproduct of its metabolism by jmstickney on Tuesday June 14, 2016 @01:00PM (#11903396)
Like the mindset that eating fat directly makes a person increase fat percentage. Similarly to the idea around cholesterol.
Re:Ketamine lifts depression via a byproduct of its metabolism by openasocket on Tuesday June 14, 2016 @12:34PM (#11903196)
At the risk of making an appeal to authority, I got that quote from a clinical psychologist, referring to the effect of alcohol on clinical depression. See my other comment for an explanation.
Re:Ketamine lifts depression via a byproduct of its metabolism by pierrec on Tuesday June 14, 2016 @12:41PM (#11903234)
I see, it makes more sense when you make it more explicit. But then I also have an appeal to authority: the majority of drugs prescribed against depression also happen to be depressants. And sometimes it works, though they all tend to have addiction and habituation potentials as well. I would say the psychologist you're quoting is raising a point that goes against the mainstream, which is not necessarily bad of course, but the phrase in itself remains a (somewhat misleading) play on words.
Re:Ketamine lifts depression via a byproduct of its metabolism by openasocket on Tuesday June 14, 2016 @01:10PM (#11903472)
>the majority of drugs prescribed against depression also happen to be depressants

Can you give a source for that, and some examples? I couldn't find anything (googling "antidepressant depressant" is about as helpful as you'd think).

I'd still argue that the effects of depressants (the inhibition of neurotransmission) are in and of themselves not helpful for people depression.

I agree my phrasing was a bit confusing, I tend to value poignancy over explicitness :)

Re:Ketamine lifts depression via a byproduct of its metabolism by pierrec on Tuesday June 14, 2016 @01:45PM (#11903814)
>Can you give a source for that

I guess it depends on how strict you are with your definition of a depressant, but looking at this list:

http://www.webmd.com/drugs/condition-1022-depression.aspx

If you establish a depressant <-> stimulant axis, the major drugs here are very much on the depressant side. As for their effectiveness, depressants generally feature a euphoric, "feel good" component. From there it's easy to see how some members of this class might be helpful against depression. It seems paradoxical that you might be worsening the lethargic aspect, but basically the treatment concentrates on the negative mood, loss of pleasure aspect, which appears to be a more effective way of approaching the problem (if you take for granted that chemicals are a good approach at all).