Anything you want. Dependency management is taken care of by a simple `pip install flask`, or a requirements.txt. The rest depends on the packages you are using.

> It takes a lot more work to build a yelp clone with python than it does with react.

And why do you think that? I could build a simple and performant Yelp clone with full authentication, admin access, and persistence using only a handful of Python packages:

* Flask: web app microframework

* Jinja2: view templating language

* SQLAlchemy: database ORM

* Psycopg: Postgres database driver

* Flask-SQLAlchemy: Flask plugin for SQLAlchemy

* Flask-Login: authentication, accounts

* Flask-Admin: administration

Of course, just like in the case of React, you'd need HTML + CSS for styling, and JS in case you'd like interactive elements. And finally, to run the app in production, I'd use Nginx + uWSGI.

And what if I want to use multiple versions of a given library for my development? Suddenly I'm learning virtualenv...