pcrh

Looking-up DCTN1 on genecards, a popular site that collates known gene-function relationships, shows that it is already known to be associated with Parkinson's-like conditions [0]. Similarly on Uniprot [2].

[0] https://www.genecards.org/card/DCTN1#Phenotypes

[1] https://www.uniprot.org/uniprotkb/Q14203/entry#disease_varia...

The article mentions that Cellebrite managed to gain access to the phone. Does anyone know how they did this?

If they were able, why would the UK government, or any other government, not also be able?

This is frankly quite worrisome for democracy.

Imagine this kind of method being deployed at scale to influence elections... no doubt it is already happening...

Did you read the article? It claims that LLMs lie more convincingly than humans.

People who...

You remind me that France had (maybe still does?) national dictation competitions (championnat national de dictées). Much of French orthography is silent, so can be a real challenge!

Here are a few additional reports:

>1. Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis. Conclusions: SSRIs might have statistically significant effects on depressive symptoms, but *all trials were at high risk of bias and the clinical significance seems questionable*. SSRIs significantly increase the risk of both serious and non-serious adverse events. The potential small beneficial effects seem to be outweighed by harmful effects.

>2. The trouble with antidepressants: why the evidence overplays benefits and underplays risks. Widespread prescribing has not reduced mental disability or suicide, raising questions about the assessment of evidence on effectiveness and safety of antidepressants

>3. In search of a dose–response relationship in SSRIs—a systematic review, meta-analysis, and network meta-analysis. Conclusions: There is no conclusive level I or level II evidence of a clinically meaningful dose–response relationship of SSRIs as a group or of single substances. High SSRI doses are not recommended as routine treatment.

>4 The serotonin theory of depression: a systematic umbrella review of the evidence "We did not identify *any* trials using ‘active placebo’ or ‘no intervention’ as control interventions. "

[1] https://pubmed.ncbi.nlm.nih.gov/28178949/

[2] https://www.bmj.com/content/370/bmj.m3200

[3] https://pubmed.ncbi.nlm.nih.gov/32970827/

[4] https://pubmed.ncbi.nlm.nih.gov/35854107/

Inventorship of patents has a clear legal basis, and is quite different from the basis of scientific authorship.

The system disincentifies adding "ghost" inventors since incorrect listing of the inventors can invalidate a patent.

So, yes, it's likely that the patent attorneys hired by Stanford advised that only Page should be listed as an inventor. Stanford gets its money via the assignment, not the inventor list.

The changes to old.reddit mean I've started using redlib.catsarch for simple browsing.

The EU won't take anyone to the ECHR.

EU laws are adjudicated by the Court of Justice of the European Union.

https://en.wikipedia.org/wiki/European_Court_of_Justice

Complaining about the ECHR in the same breath as the EU is one of the telltale signs of psyops influence.

The ECHR has nothing to do with the EU.

Interesting article!

I was curious as to the debate surrounding the authenticity of the Ram Khamhaeng stele, but with a quick search was not able to find a definitive answer...

Such verbal offers can be binding in law, but fortunately for Derek Nolan he didn't mention a price. Otherwise he might have found himself in the same hot water as Elon Musk did when he offered to buy Twitter.

Link to the original study below, free to access [0]. The key data appear to be this:

>At baseline, 184 (14%) of 1280 children with successful FEV1 measurement in London had a clinically low FEV1 (pre-bronchodilator FEV1 <80% of predicted value) compared with 126 (9%) of 1339 children in Luton (appendix p 8). At the end of the study, these values had dropped to 51 (9%) of 585 children in London and 41 (7%) of 606 children in Luton (appendix p 8).

So the proportion of children with low lung function dropped from 14% to 9% in London, and from 9% to 7% at the comparator site in Luton. It's not that much different, though any improvement is obviously welcome.

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2...

I wonder how the court became aware of this attempt?

It might be as simple as a clerk doing "select all" and noticing the extra selection?

Or what else?

That's the source of emission by the cow or steer. Industrial processing of the dung produces vastly more.

Table 3 in this source [0] shows enteric vs manure methane emissions are 158 vs 137 kg CH4/yr for dairy cows, who are mostly fed in feedlots, and 58 vs 2.4 for meat and other cattle, in the US and Canada. So the CH4 emissions range 65-fold from 2.4 to 158 depending on how the cattle are farmed.

[0] Revised methane emissions factors and spatially distributed annual carbon fluxes for global livestock. https://pmc.ncbi.nlm.nih.gov/articles/pmid/28959823/

Animal-emitted CO2 isn't the problem, but methane.

The CO2 captured by plants and eaten by livestock gets converted in part to methane, a more more potent greenhouse gas. This does eventually degrade back to the original CO2, but on a scale of decades, it's currently too slow to prevent accumulation of methane.

Stockyards are the worst offenders. This is due to how the dung is processed, which releases a lot of methane. Grass-fed cattle have much lower net emissions of greenhouse gasses.

It isn't the "cow farts" that produce most methane, but rather the anaerobic processing of cow dung emanating from feed lots, dairy operations, etc.

Grass-fed beef cattle whose dung is "recycled" in a more natural way in the fields produce the same emissions as would wild ruminants such as antelope, bison, etc.

The biodiversity problem in the above refers mostly to new land clearances intended for farming, including for feedstock. This is minor in N. America and Europe, mostly as the clearances were done decades or over a century ago.

Agreed. The audience here tends towards functional/technical writing rather than expressive writing.

On the other hand, should an article about typography be posted, then there will be many comments regarding the nuances of serifs, kerning, spacing and ligatures. Ignoring of course that none of these change the facts/data being communicated!

Browsing that site, The SETI Institute appears to have expanded beyond its original goal of finding extraterrestrial intelligence into astrobiology and more. Perhaps the first attempts at detecting alien radio signals hoped too much?

I have little doubt that, given the infinite size of the universe, that extraterrestrial intelligence (of some sort) exists, the question is whether we will ever detect it... It perhaps even exists as close to us as Europa, should we attempt a landing there...

Related, I recently read an article about staghorn corals surviving in Miami of all places [1]. They resisted bleaching, pollution and inundations with fresh water. The origin of this resistance is apparently colonization by a different species of algae that is otherwise native to the western Pacific and Indian Oceans.

[1] https://www.biographic.com/the-corals-that-shouldnt-exist/

>I can't imagine that the same factors aren't at play in the scientific research community

I can't speak for the entire scientific research community, but I can say that for basic biomedical research (not clinical research), LLMs are mostly ignored. They simply don't have the ability to parse most raw wet lab data.

This obviously has not stopped the creation of a legion of startups, new Asst Profs, etc, claiming that they are using "AI" to crack new frontiers. In practice, the most effective of these use machine learning, rather than LLMs.

>“We can do neuroscience on A.I. systems in a way that we kind of can’t with humans,” Mr. Long said, in that they “don’t have skulls.” The three jobs Eleos was hiring for would all be machine-learning research scientists who could design and perform experiments.

This is pretty interesting! I wouldn't know how easy such "surgery" on LLMs would be to do, if if they do have "knowledge" or "consciousness" as their proponents claim, there could be some profound outcomes from this.

I would have thought that the right to privacy as a fundamental human right would have been sufficient. But apparently not....

Equally, there is abundant precedent for forbidding interference with old-fashioned postal communications, that seemingly doesn't translate to electronic communications...

There's a risk of echos of Theranos here. A paper apparently describing this ultrasound approach has been uploaded to arXiv [0]. If so, the resolution demonstrated is nowhere near sufficient to detect small changes to anatomy, let alone monitor them over time. Future developments could obviously improve on that.

[0] “Whole Cross-Sectional Human Ultrasound Tomography” https://arxiv.org/pdf/2307.00110

This prompted me to check out rental rates in my old haunt of Inner Sunset. I remember the Craigslist offices on 9th and Judah...

It's shocking that a 1 bedroom apartment now rents for $4-5k/month....

You will notice that the criticism this judgement receives if not for finding Song guilty, even if the sentence is inordinately long for a non-lethal crime with minor wider repercussions.

The criticism this judgement receives is the fact that the prosecutors and judge drew these lines of association into a "terrorist organization" so much that even merely possessing literature tangentially related to this non-existent "organization" was deemed a crime worthy of 30 years imprisonment. This is the sort of thinking that sent people to the Soviet Gulags.

It's kind of fact-based that "antifa" is not an organization in the real world.

It's as real as claiming that "pro-gun" is an organization, or "anti-pollution" is an organization.

The zines are only evidence of Rueda's political opinions, not of intent to carry out a crime.