Lol_arco
Re:Ask HN: I am at a loss. What shall I do?
on Friday April 25, 2025 @04:15AM (#43791388)
This is the answer. Take a moment, get a job, regroup and mourn your losses. Your well being is paramount, OP.
Re:AI-Designed Antivenoms: New Proteins to Block Deadly Snake Toxins
on Saturday April 19, 2025 @02:28PM (#43738346)
Yeah there isn't enough money in it for big pharma. Maybe some other form of funding, but this is the reason why all these tropical diseases are neglected.
Re:AI-Designed Antivenoms: New Proteins to Block Deadly Snake Toxins
on Saturday April 19, 2025 @06:50AM (#43735556)
Yeah David Baker and co. are using a lot of diffusion models for their research!
And yeah some of these mice results are very good, and hopefully they translate to a good degree to humans
Re:AI-Designed Antivenoms: New Proteins to Block Deadly Snake Toxins
on Saturday April 19, 2025 @06:47AM (#43735548)
Yes you're right! It's very hard to estimate how many people die from snake bite, for a thousand reasons (under reporting, incomplete snake databases, etc). This meta analysis indeed puts the numbers above 100.000 https://pmc.ncbi.nlm.nih.gov/articles/PMC11020954/ but I get where you're coming from! The uncertainty in these data is huge.