As suggested above RoR (ruby on rails) would be a good starting point. The js world is changing to fast to really sink your teeth into one framework. Even angular is about to get dumped. Maybe it would be wise to jump on a new framework pre-production stage and grow with it. Such as http://aurelia.io/ . I say this because you will likely get a good life span out of a new framework rather then one of the old dogs dying out right now.