Some general comments I have on the article (which I thought in general was very good):

- At 80,000 Hours (the social impact career advice service I cofounded) we don't advise that many people to aim to earn to give in the long-term; less than a third of the people who have changed their plans on the basis of our advice have done so in the past, and the proportion will be less in the long-term.

- Most commonly, the people who do this are those who really wanted to work in lucrative career X anyway, but were thinking of doing something else. E.g. Matt Gibb really wanted to do startups, but thought he should instead do something 'more ethical'; our advice made him realise he could do both. He's pledging 30% of his equity at LendLayer. (interview here: https://80000hours.org/2014/02/interview-with-matt-gibb/)

- Another common strategy (which we do recommend) is to gain skills in a for-profit company before then moving to something with greater direct impact afterwards. While you're working for that for-profit, you may as well be donating a lot too!

- if you think this is cool and are an entrepreneur, you might want to take the Founders Pledge (http://thefounderspledge.org/about/)

- if you think this is cool and can't or don't want to take the Founders Pledge, you might want to take the Giving What We Can pledge (disclaimer: i cofounded GWWC) https://www.givingwhatwecan.org/get-involved/become-member

- If you think this is cool and aren't sure what you should do with your life, then we can advise you at 80,000 Hours (https://80000hours.org/). We're currently in Mountain View for the summer.

Some of the charities mentioned are clearly advocating for policy change (lifting copyright and restructured tax schemes), and I think that generally all charities must decide how to relate to the current structure of the world because whatever the ill you are campaigning against preventive measure are most effective at preventing suffering. So one question is if you see any natural limit for when something goes from a charity to a political campaign and vice versa. For instance, imagine the bizarre scenario where a presidential candidate pledges a significant increase to foreign humanitarian aid by taking from the foreign military aid budget. Will make that candidacy a worthwhile charity (supposing the bizarro candidate has reasonable probability of winning)?

An unrelated question is: why do you think there are so few investment opportunities that are truly concerned with being ethical? The GiveWell founders seems like they could have made an investment fund dedicated to growing local companies in the poorer parts of the world. Direct cash transfers are among the best ways of helping the poor, but stable financing with modest return expectations seems like it could be pretty good too, with the benefit of slightly growing the capital available to help. Or you could imagine getting a significant amount of shares in Shell and turn up at shareholders meetings and make them repair their pipelines properly and such things.

Re: bizarro candidate? Yes, certainly. (as long as they're actually going to be much better for the world and your donation will make a difference). Lower probability of larger upside can easily beat guarantee of doing more modest amount of good.

There's a lot of talk about 'impact investing' and I see potential there, but at the moment the 'impact' side of things is generally very poorly understood so it's not fulfilling its potential in my view.