I honestly can't remember where this knowledge comes from. My feeling is i learned it on my oncology term 12 months ago. It may have even been a ipilimumab biosimilar. Unfortunately google is mostly saturated with success stories and papers relating to monoclonal antibodies and wherever I heard about the writeup of the failure has vanished into the nether-regions of google.

Apologies. If anything comes up, put a contact email in your details and i'll reach out to you.