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Re:Twilio Video – Real-time WebRTC video infrastructure by emcho on Tuesday April 14, 2015 @05:30PM (#9377501)
Jitsi Videobridge has both of those.
Re:Twilio Video – Real-time WebRTC video infrastructure by kolencherry on Thursday April 16, 2015 @01:58PM (#9389609)
Jitsi only does the audio portion. There's no support for layouts/video mixing.

"Jitsi Videobridge does not mix the video channels into a composite video stream, but only relays the received video channels to all call participants."