I was afflicted with having to read "Portrait of the Artist as a Young Man" in high school. In it, Joyce puts forth his theory of art - that to be pure art, it should cause no response whatsoever in the viewer. Joyce is a great writer, and was able to achieve the effect he wanted - to write a book that produces no response whatsoever in the reader (other than the feeling of revulsion at being forced to waste my time reading it). But because his theory of art is rubbish, he wastes his talent producing "art" that is a complete waste, both of his talent and of the reader's time.
The tragedy of Portrait is that so many people read it as if it were simple autobiography. It isn't. Stephen is based on the young Joyce, yes, and in the original draft and notes (mostly destroyed, published as Stephen Hero) there's a saccharine sincerity that fits your sense of the book a little better.
But that's not the finished Portrait. In Portrait Joyce makes fun of himself. He's critical of his youthful exuberance. It's a hilarious book for anyone who's ever taken themselves too seriously, which, I think, is all of us.
At any rate, even if that really was the goal he set for himself, he failed. Ulysses elicited a wide range of responses from me.
I mean, there was a scene or two in Portrait that I responded to, too. But mainly, it was a protagonist I didn't care about, doing things I didn't care about, with other people I didn't care about, in places I didn't care about. So "no response whatsoever" is a pretty fair summary of my reaction.
They might have. Especially Pynchon, but Joyce too.